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Structural diversity of B-cell receptor repertoires along the B-cell differentiation axis in humans and mice

Most current analysis tools for antibody next-generation sequencing data work with primary sequence descriptors, leaving accompanying structural information unharnessed. We have used novel rapid methods to structurally characterize the complementary-determining regions (CDRs) of more than 180 millio...

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Detalles Bibliográficos
Autores principales:	Kovaltsuk, Aleksandr, Raybould, Matthew I. J., Wong, Wing Ki, Marks, Claire, Kelm, Sebastian, Snowden, James, Trück, Johannes, Deane, Charlotte M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048297/ https://www.ncbi.nlm.nih.gov/pubmed/32069281 http://dx.doi.org/10.1371/journal.pcbi.1007636

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