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An activator of G protein-coupled receptor and MEK1/2-ERK1/2 signaling inhibits HIV-1 replication by altering viral RNA processing
The ability of HIV-1 to evolve resistance to combined antiretroviral therapies (cARTs) has stimulated research into alternative means of controlling this infection. We assayed >60 modulators of RNA alternative splicing (AS) to identify new inhibitors of HIV-1 RNA processing—a segment of the viral...
Autores principales: | Wong, Raymond W., Balachandran, Ahalya, Cheung, Peter K., Cheng, Ran, Pan, Qun, Stoilov, Peter, Harrigan, P. Richard, Blencowe, Benjamin J., Branch, Donald R., Cochrane, Alan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048317/ https://www.ncbi.nlm.nih.gov/pubmed/32069328 http://dx.doi.org/10.1371/journal.ppat.1008307 |
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