Cytoprotective Activity of Ethylacetate Fraction of Picria fel-terrae Lour. Herbs

AIM: Free radicals produce from metabolism or enviromental which interact continously with biological system. Picria fel-terrae Lour. herbs have been used as antioxidant and treat various diseases. The aim of this study was to evaluate cytoprotective activity of ethylacetate fraction (EAF) of Picria...

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Detalles Bibliográficos
Autores principales: Satria, Denny, Silalahi, Jansen, Haro, Ginda, Ilyas, Syafruddin, Hasibuan, Poppy Anjelisa Zaitun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Republic of Macedonia 2019
Materias:
Herbal Medicine in Pharmaceutical and Clinical Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048334/
https://www.ncbi.nlm.nih.gov/pubmed/32127993
http://dx.doi.org/10.3889/oamjms.2019.521
Descripción
Sumario:AIM: Free radicals produce from metabolism or enviromental which interact continously with biological system. Picria fel-terrae Lour. herbs have been used as antioxidant and treat various diseases. The aim of this study was to evaluate cytoprotective activity of ethylacetate fraction (EAF) of Picria fel-terrae Lour. herbs. METHODS: Cytoprotective activity were determined by MTT asay and flow cytometry assay on Vero cells which induced with H(2)O(2) 0.8 mM. RESULTS: EAF at 100 µg/mL were showed highest viability (88.83 ± 2.90%) and ROS expression (66.75%) on Vero cells. CONCLUSION: EAF of Picria fel-terrae Lour. herbs have cytoprotective activity.

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