Cargando…

Cytoprotective Activity of Ethylacetate Fraction of Picria fel-terrae Lour. Herbs

AIM: Free radicals produce from metabolism or enviromental which interact continously with biological system. Picria fel-terrae Lour. herbs have been used as antioxidant and treat various diseases. The aim of this study was to evaluate cytoprotective activity of ethylacetate fraction (EAF) of Picria...

Descripción completa

Detalles Bibliográficos
Autores principales: Satria, Denny, Silalahi, Jansen, Haro, Ginda, Ilyas, Syafruddin, Hasibuan, Poppy Anjelisa Zaitun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Republic of Macedonia 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048334/
https://www.ncbi.nlm.nih.gov/pubmed/32127993
http://dx.doi.org/10.3889/oamjms.2019.521
_version_ 1783502282142253056
author Satria, Denny
Silalahi, Jansen
Haro, Ginda
Ilyas, Syafruddin
Hasibuan, Poppy Anjelisa Zaitun
author_facet Satria, Denny
Silalahi, Jansen
Haro, Ginda
Ilyas, Syafruddin
Hasibuan, Poppy Anjelisa Zaitun
author_sort Satria, Denny
collection PubMed
description AIM: Free radicals produce from metabolism or enviromental which interact continously with biological system. Picria fel-terrae Lour. herbs have been used as antioxidant and treat various diseases. The aim of this study was to evaluate cytoprotective activity of ethylacetate fraction (EAF) of Picria fel-terrae Lour. herbs. METHODS: Cytoprotective activity were determined by MTT asay and flow cytometry assay on Vero cells which induced with H(2)O(2) 0.8 mM. RESULTS: EAF at 100 µg/mL were showed highest viability (88.83 ± 2.90%) and ROS expression (66.75%) on Vero cells. CONCLUSION: EAF of Picria fel-terrae Lour. herbs have cytoprotective activity.
format Online
Article
Text
id pubmed-7048334
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Republic of Macedonia
record_format MEDLINE/PubMed
spelling pubmed-70483342020-03-03 Cytoprotective Activity of Ethylacetate Fraction of Picria fel-terrae Lour. Herbs Satria, Denny Silalahi, Jansen Haro, Ginda Ilyas, Syafruddin Hasibuan, Poppy Anjelisa Zaitun Open Access Maced J Med Sci Herbal Medicine in Pharmaceutical and Clinical Sciences AIM: Free radicals produce from metabolism or enviromental which interact continously with biological system. Picria fel-terrae Lour. herbs have been used as antioxidant and treat various diseases. The aim of this study was to evaluate cytoprotective activity of ethylacetate fraction (EAF) of Picria fel-terrae Lour. herbs. METHODS: Cytoprotective activity were determined by MTT asay and flow cytometry assay on Vero cells which induced with H(2)O(2) 0.8 mM. RESULTS: EAF at 100 µg/mL were showed highest viability (88.83 ± 2.90%) and ROS expression (66.75%) on Vero cells. CONCLUSION: EAF of Picria fel-terrae Lour. herbs have cytoprotective activity. Republic of Macedonia 2019-11-14 /pmc/articles/PMC7048334/ /pubmed/32127993 http://dx.doi.org/10.3889/oamjms.2019.521 Text en Copyright: © 2019 Denny Satria, Jansen Silalahi, Ginda Haro, Syafruddin Ilyas, Poppy Anjelisa Zaitun Hasibuan. http://creativecommons.org/licenses/CC BY-NC/4.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC 4.0)
spellingShingle Herbal Medicine in Pharmaceutical and Clinical Sciences
Satria, Denny
Silalahi, Jansen
Haro, Ginda
Ilyas, Syafruddin
Hasibuan, Poppy Anjelisa Zaitun
Cytoprotective Activity of Ethylacetate Fraction of Picria fel-terrae Lour. Herbs
title Cytoprotective Activity of Ethylacetate Fraction of Picria fel-terrae Lour. Herbs
title_full Cytoprotective Activity of Ethylacetate Fraction of Picria fel-terrae Lour. Herbs
title_fullStr Cytoprotective Activity of Ethylacetate Fraction of Picria fel-terrae Lour. Herbs
title_full_unstemmed Cytoprotective Activity of Ethylacetate Fraction of Picria fel-terrae Lour. Herbs
title_short Cytoprotective Activity of Ethylacetate Fraction of Picria fel-terrae Lour. Herbs
title_sort cytoprotective activity of ethylacetate fraction of picria fel-terrae lour. herbs
topic Herbal Medicine in Pharmaceutical and Clinical Sciences
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048334/
https://www.ncbi.nlm.nih.gov/pubmed/32127993
http://dx.doi.org/10.3889/oamjms.2019.521
work_keys_str_mv AT satriadenny cytoprotectiveactivityofethylacetatefractionofpicriafelterraelourherbs
AT silalahijansen cytoprotectiveactivityofethylacetatefractionofpicriafelterraelourherbs
AT haroginda cytoprotectiveactivityofethylacetatefractionofpicriafelterraelourherbs
AT ilyassyafruddin cytoprotectiveactivityofethylacetatefractionofpicriafelterraelourherbs
AT hasibuanpoppyanjelisazaitun cytoprotectiveactivityofethylacetatefractionofpicriafelterraelourherbs