Cargando…

Optimization of SRC (Semi Refined Carrageenan) and Glucomannan Concentration as Gelling Agent to the Physical Stability Sunscreen Gel of Dry Corncob Extract (Zea mays L.)

BACKGROUND: Corncob is one of crude drug which containing phenolic compounds that can be used as an active ingredient for sunscreen preparations. In this study, extracts of dried corn cob made into a gel formulation using SRC (Semi Refined Carrageenan) and glucomannan as a gelling agent. AIM: This s...

Descripción completa

Detalles Bibliográficos
Autores principales: Yati, Kori, Srifiana, Yudi, Lestari, Asri Indah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Republic of Macedonia 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048369/
https://www.ncbi.nlm.nih.gov/pubmed/32127986
http://dx.doi.org/10.3889/oamjms.2019.514
_version_ 1783502290350505984
author Yati, Kori
Srifiana, Yudi
Lestari, Asri Indah
author_facet Yati, Kori
Srifiana, Yudi
Lestari, Asri Indah
author_sort Yati, Kori
collection PubMed
description BACKGROUND: Corncob is one of crude drug which containing phenolic compounds that can be used as an active ingredient for sunscreen preparations. In this study, extracts of dried corn cob made into a gel formulation using SRC (Semi Refined Carrageenan) and glucomannan as a gelling agent. AIM: This study aims to determine the optimal concentration of SRC (Semi Refined Carrageenan) and glucomannan to the physical stability of the gel. METHODS: Gel made into four formulas with a ratio of 1: 4 and the concentration of each formula was 1%, 1.5%, 2%, 2.5%. Each formula was evaluated for 6 weeks of storage that includes organoleptic test, homogeneity, pH, viscosity, dispersive power, freeze-thaw test and centrifugation. RESULTS: The results showed the fourth formula did not change the organoleptic test and homogeneity test. In the test separation of the freeze-thaw method, the fourth formula was stable, while in the centrifugation test formula 1 and 2 was been separation. pH and viscosity results obtained from statistics with a two-way ANOVA showed significant differences in each formula. CONCLUSION: From the results of this study concluded that the formula 3 with a concentration of 2% was the optimal concentration as a gelling agent.
format Online
Article
Text
id pubmed-7048369
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Republic of Macedonia
record_format MEDLINE/PubMed
spelling pubmed-70483692020-03-03 Optimization of SRC (Semi Refined Carrageenan) and Glucomannan Concentration as Gelling Agent to the Physical Stability Sunscreen Gel of Dry Corncob Extract (Zea mays L.) Yati, Kori Srifiana, Yudi Lestari, Asri Indah Open Access Maced J Med Sci Herbal Medicine in Pharmaceutical and Clinical Sciences BACKGROUND: Corncob is one of crude drug which containing phenolic compounds that can be used as an active ingredient for sunscreen preparations. In this study, extracts of dried corn cob made into a gel formulation using SRC (Semi Refined Carrageenan) and glucomannan as a gelling agent. AIM: This study aims to determine the optimal concentration of SRC (Semi Refined Carrageenan) and glucomannan to the physical stability of the gel. METHODS: Gel made into four formulas with a ratio of 1: 4 and the concentration of each formula was 1%, 1.5%, 2%, 2.5%. Each formula was evaluated for 6 weeks of storage that includes organoleptic test, homogeneity, pH, viscosity, dispersive power, freeze-thaw test and centrifugation. RESULTS: The results showed the fourth formula did not change the organoleptic test and homogeneity test. In the test separation of the freeze-thaw method, the fourth formula was stable, while in the centrifugation test formula 1 and 2 was been separation. pH and viscosity results obtained from statistics with a two-way ANOVA showed significant differences in each formula. CONCLUSION: From the results of this study concluded that the formula 3 with a concentration of 2% was the optimal concentration as a gelling agent. Republic of Macedonia 2019-11-14 /pmc/articles/PMC7048369/ /pubmed/32127986 http://dx.doi.org/10.3889/oamjms.2019.514 Text en Copyright: © 2019 Kori Yati, Yudi Srifiana, Asri Indah Lestari. http://creativecommons.org/licenses/CC BY-NC/4.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC 4.0)
spellingShingle Herbal Medicine in Pharmaceutical and Clinical Sciences
Yati, Kori
Srifiana, Yudi
Lestari, Asri Indah
Optimization of SRC (Semi Refined Carrageenan) and Glucomannan Concentration as Gelling Agent to the Physical Stability Sunscreen Gel of Dry Corncob Extract (Zea mays L.)
title Optimization of SRC (Semi Refined Carrageenan) and Glucomannan Concentration as Gelling Agent to the Physical Stability Sunscreen Gel of Dry Corncob Extract (Zea mays L.)
title_full Optimization of SRC (Semi Refined Carrageenan) and Glucomannan Concentration as Gelling Agent to the Physical Stability Sunscreen Gel of Dry Corncob Extract (Zea mays L.)
title_fullStr Optimization of SRC (Semi Refined Carrageenan) and Glucomannan Concentration as Gelling Agent to the Physical Stability Sunscreen Gel of Dry Corncob Extract (Zea mays L.)
title_full_unstemmed Optimization of SRC (Semi Refined Carrageenan) and Glucomannan Concentration as Gelling Agent to the Physical Stability Sunscreen Gel of Dry Corncob Extract (Zea mays L.)
title_short Optimization of SRC (Semi Refined Carrageenan) and Glucomannan Concentration as Gelling Agent to the Physical Stability Sunscreen Gel of Dry Corncob Extract (Zea mays L.)
title_sort optimization of src (semi refined carrageenan) and glucomannan concentration as gelling agent to the physical stability sunscreen gel of dry corncob extract (zea mays l.)
topic Herbal Medicine in Pharmaceutical and Clinical Sciences
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048369/
https://www.ncbi.nlm.nih.gov/pubmed/32127986
http://dx.doi.org/10.3889/oamjms.2019.514
work_keys_str_mv AT yatikori optimizationofsrcsemirefinedcarrageenanandglucomannanconcentrationasgellingagenttothephysicalstabilitysunscreengelofdrycorncobextractzeamaysl
AT srifianayudi optimizationofsrcsemirefinedcarrageenanandglucomannanconcentrationasgellingagenttothephysicalstabilitysunscreengelofdrycorncobextractzeamaysl
AT lestariasriindah optimizationofsrcsemirefinedcarrageenanandglucomannanconcentrationasgellingagenttothephysicalstabilitysunscreengelofdrycorncobextractzeamaysl