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Optimization of SRC (Semi Refined Carrageenan) and Glucomannan Concentration as Gelling Agent to the Physical Stability Sunscreen Gel of Dry Corncob Extract (Zea mays L.)
BACKGROUND: Corncob is one of crude drug which containing phenolic compounds that can be used as an active ingredient for sunscreen preparations. In this study, extracts of dried corn cob made into a gel formulation using SRC (Semi Refined Carrageenan) and glucomannan as a gelling agent. AIM: This s...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Republic of Macedonia
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048369/ https://www.ncbi.nlm.nih.gov/pubmed/32127986 http://dx.doi.org/10.3889/oamjms.2019.514 |
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author | Yati, Kori Srifiana, Yudi Lestari, Asri Indah |
author_facet | Yati, Kori Srifiana, Yudi Lestari, Asri Indah |
author_sort | Yati, Kori |
collection | PubMed |
description | BACKGROUND: Corncob is one of crude drug which containing phenolic compounds that can be used as an active ingredient for sunscreen preparations. In this study, extracts of dried corn cob made into a gel formulation using SRC (Semi Refined Carrageenan) and glucomannan as a gelling agent. AIM: This study aims to determine the optimal concentration of SRC (Semi Refined Carrageenan) and glucomannan to the physical stability of the gel. METHODS: Gel made into four formulas with a ratio of 1: 4 and the concentration of each formula was 1%, 1.5%, 2%, 2.5%. Each formula was evaluated for 6 weeks of storage that includes organoleptic test, homogeneity, pH, viscosity, dispersive power, freeze-thaw test and centrifugation. RESULTS: The results showed the fourth formula did not change the organoleptic test and homogeneity test. In the test separation of the freeze-thaw method, the fourth formula was stable, while in the centrifugation test formula 1 and 2 was been separation. pH and viscosity results obtained from statistics with a two-way ANOVA showed significant differences in each formula. CONCLUSION: From the results of this study concluded that the formula 3 with a concentration of 2% was the optimal concentration as a gelling agent. |
format | Online Article Text |
id | pubmed-7048369 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Republic of Macedonia |
record_format | MEDLINE/PubMed |
spelling | pubmed-70483692020-03-03 Optimization of SRC (Semi Refined Carrageenan) and Glucomannan Concentration as Gelling Agent to the Physical Stability Sunscreen Gel of Dry Corncob Extract (Zea mays L.) Yati, Kori Srifiana, Yudi Lestari, Asri Indah Open Access Maced J Med Sci Herbal Medicine in Pharmaceutical and Clinical Sciences BACKGROUND: Corncob is one of crude drug which containing phenolic compounds that can be used as an active ingredient for sunscreen preparations. In this study, extracts of dried corn cob made into a gel formulation using SRC (Semi Refined Carrageenan) and glucomannan as a gelling agent. AIM: This study aims to determine the optimal concentration of SRC (Semi Refined Carrageenan) and glucomannan to the physical stability of the gel. METHODS: Gel made into four formulas with a ratio of 1: 4 and the concentration of each formula was 1%, 1.5%, 2%, 2.5%. Each formula was evaluated for 6 weeks of storage that includes organoleptic test, homogeneity, pH, viscosity, dispersive power, freeze-thaw test and centrifugation. RESULTS: The results showed the fourth formula did not change the organoleptic test and homogeneity test. In the test separation of the freeze-thaw method, the fourth formula was stable, while in the centrifugation test formula 1 and 2 was been separation. pH and viscosity results obtained from statistics with a two-way ANOVA showed significant differences in each formula. CONCLUSION: From the results of this study concluded that the formula 3 with a concentration of 2% was the optimal concentration as a gelling agent. Republic of Macedonia 2019-11-14 /pmc/articles/PMC7048369/ /pubmed/32127986 http://dx.doi.org/10.3889/oamjms.2019.514 Text en Copyright: © 2019 Kori Yati, Yudi Srifiana, Asri Indah Lestari. http://creativecommons.org/licenses/CC BY-NC/4.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC 4.0) |
spellingShingle | Herbal Medicine in Pharmaceutical and Clinical Sciences Yati, Kori Srifiana, Yudi Lestari, Asri Indah Optimization of SRC (Semi Refined Carrageenan) and Glucomannan Concentration as Gelling Agent to the Physical Stability Sunscreen Gel of Dry Corncob Extract (Zea mays L.) |
title | Optimization of SRC (Semi Refined Carrageenan) and Glucomannan Concentration as Gelling Agent to the Physical Stability Sunscreen Gel of Dry Corncob Extract (Zea mays L.) |
title_full | Optimization of SRC (Semi Refined Carrageenan) and Glucomannan Concentration as Gelling Agent to the Physical Stability Sunscreen Gel of Dry Corncob Extract (Zea mays L.) |
title_fullStr | Optimization of SRC (Semi Refined Carrageenan) and Glucomannan Concentration as Gelling Agent to the Physical Stability Sunscreen Gel of Dry Corncob Extract (Zea mays L.) |
title_full_unstemmed | Optimization of SRC (Semi Refined Carrageenan) and Glucomannan Concentration as Gelling Agent to the Physical Stability Sunscreen Gel of Dry Corncob Extract (Zea mays L.) |
title_short | Optimization of SRC (Semi Refined Carrageenan) and Glucomannan Concentration as Gelling Agent to the Physical Stability Sunscreen Gel of Dry Corncob Extract (Zea mays L.) |
title_sort | optimization of src (semi refined carrageenan) and glucomannan concentration as gelling agent to the physical stability sunscreen gel of dry corncob extract (zea mays l.) |
topic | Herbal Medicine in Pharmaceutical and Clinical Sciences |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048369/ https://www.ncbi.nlm.nih.gov/pubmed/32127986 http://dx.doi.org/10.3889/oamjms.2019.514 |
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