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Mesoscale All-Atom Influenza Virus Simulations Suggest New Substrate Binding Mechanism
[Image: see text] Influenza virus circulates in human, avian, and swine hosts, causing seasonal epidemic and occasional pandemic outbreaks. Influenza neuraminidase, a viral surface glycoprotein, has two sialic acid binding sites. The catalytic (primary) site, which also binds inhibitors such as osel...
Autores principales: | Durrant, Jacob D., Kochanek, Sarah E., Casalino, Lorenzo, Ieong, Pek U., Dommer, Abigail C., Amaro, Rommie E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048371/ https://www.ncbi.nlm.nih.gov/pubmed/32123736 http://dx.doi.org/10.1021/acscentsci.9b01071 |
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