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Integrated analysis of H2A.Z isoforms function reveals a complex interplay in gene regulation

The H2A.Z histone variant plays major roles in the control of gene expression. In human, H2A.Z is encoded by two genes expressing two isoforms, H2A.Z.1 and H2A.Z.2 differing by three amino acids. Here, we undertook an integrated analysis of their functions in gene expression using endogenously-tagge...

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Detalles Bibliográficos
Autores principales: Lamaa, Assala, Humbert, Jonathan, Aguirrebengoa, Marion, Cheng, Xue, Nicolas, Estelle, Côté, Jacques, Trouche, Didier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048395/
https://www.ncbi.nlm.nih.gov/pubmed/32109204
http://dx.doi.org/10.7554/eLife.53375