Cargando…

SKA3 promotes lung adenocarcinoma metastasis through the EGFR–PI3K–Akt axis

The processes that lead to lung adenocarcinoma (LUAD) metastasis are poorly characterized. Spindle and kinetochore associated complex subunit 3 (SKA3) plays a key role in cervical cancer development, but its contribution to LUAD is unknown. Here, we found that SKA3 is overexpressed in LUAD and its e...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hu, Dan-dan, Chen, Hai-ling, Lou, Li-ming, Zhang, Hong, Yang, Guo-liang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2020
Materias:	Cancer
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048675/ https://www.ncbi.nlm.nih.gov/pubmed/32068236 http://dx.doi.org/10.1042/BSR20194335

Ejemplares similares

SKA3 promotes cell proliferation and migration in cervical cancer by activating the PI3K/Akt signaling pathway
por: Hu, Rong, et al.
Publicado: (2018)

Isoliquiritigenin inhibits the proliferation, migration and metastasis of Hep3B cells via suppressing cyclin D1 and PI3K/AKT pathway
por: Huang, Yun, et al.
Publicado: (2020)

14‐3‐3ζ promotes gliomas cells invasion by regulating Snail through the PI3K/AKT signaling
por: Li, Junjun, et al.
Publicado: (2019)

Isorhamnetin inhibited the proliferation and metastasis of androgen-independent prostate cancer cells by targeting the mitochondrion-dependent intrinsic apoptotic and PI3K/Akt/mTOR pathway
por: Cai, Fangzhen, et al.
Publicado: (2020)

Erianin induces triple-negative breast cancer cells apoptosis by activating PI3K/Akt pathway
por: Xu, Yonggang, et al.
Publicado: (2021)

SKA3 Up-regulation Promotes Lung Adenocarcinoma Growth and is a Predictor of Poor Prognosis
por: Sun, Rong-Li, et al.
Publicado: (2019)

ARHGAP42 promotes cell migration and invasion involving PI3K/Akt signaling pathway in nasopharyngeal carcinoma
por: Hu, Qian, et al.
Publicado: (2018)

Downregulation of NCL attenuates tumor formation and growth in HeLa cells by targeting the PI3K/AKT pathway
por: Ying, Jun, et al.
Publicado: (2022)

ZNF692 promotes colon adenocarcinoma cell growth and metastasis by activating the PI3K/AKT pathway
por: Xing, Yanwei, et al.
Publicado: (2019)

MiR-27a-3p enhances the cisplatin sensitivity in hepatocellular carcinoma cells through inhibiting PI3K/Akt pathway
por: Yang, Ying, et al.
Publicado: (2021)

LncRNA HAND2-AS1 inhibits proliferation and promotes apoptosis of non-small cell lung cancer cells by inactivating PI3K/Akt pathway
por: Gao, Ting, et al.
Publicado: (2020)

Digoxin exerts anticancer activity on human nonsmall cell lung cancer cells by blocking PI3K/Akt pathway
por: Wang, Yingying, et al.
Publicado: (2021)

LPCAT1 promotes gefitinib resistance via upregulation of the EGFR/PI3K/AKT signaling pathway in lung adenocarcinoma
por: Ding, Jianghua, et al.
Publicado: (2022)

Mex3a interacts with LAMA2 to promote lung adenocarcinoma metastasis via PI3K/AKT pathway
por: Liang, Jinghui, et al.
Publicado: (2020)

MiR-25-3p targets PTEN to regulate the migration, invasion, and apoptosis of esophageal cancer cells via the PI3K/AKT pathway
por: Zhang, Liang, et al.
Publicado: (2020)

Cystathionine-β-synthase is essential for AKT-induced senescence and suppresses the development of gastric cancers with PI3K/AKT activation
por: Zhu, Haoran, et al.
Publicado: (2022)

Angiotensin II enhances the proliferation of Natural Killer/T-cell lymphoma cells via activating PI3K/Akt signaling pathway
por: Zhang, Gui-Hua, et al.
Publicado: (2020)

FNDC4 acts as an extracellular factor to promote the invasiveness of hepatocellular carcinoma partly via the PI3K/Akt signalling pathway
por: Wang, Baolin, et al.
Publicado: (2021)

LPCAT1 promotes brain metastasis of lung adenocarcinoma by up-regulating PI3K/AKT/MYC pathway
por: Wei, Chunhua, et al.
Publicado: (2019)

PI3K/AKT pathway regulates E-cadherin and Desmoglein 2 in aggressive prostate cancer
por: Barber, Alison G, et al.
Publicado: (2015)

Fangchinoline exerts antitumour activity by suppressing the EGFR-PI3K/AKT signalling pathway in colon adenocarcinoma
por: Jiang, Fengqi, et al.
Publicado: (2021)

Erianin suppresses hepatocellular carcinoma cells through down-regulation of PI3K/AKT, p38 and ERK MAPK signaling pathways
por: Yang, Liang, et al.
Publicado: (2020)

MicroRNA‐4286 promotes cell proliferation, migration, and invasion via PTEN regulation of the PI3K/Akt pathway in non‐small cell lung cancer
por: Ling, Chunhua, et al.
Publicado: (2019)

miR‐107 regulates growth and metastasis of gastric cancer cells via activation of the PI3K‐AKT signaling pathway by down‐regulating FAT4
por: Wang, Li, et al.
Publicado: (2019)

Up-regulation of the PI3K/AKT and RHO/RAC/PAK signalling pathways in CHK1 inhibitor resistant Eµ-Myc lymphoma cells
por: Hunter, Jill E., et al.
Publicado: (2022)

YARS as an oncogenic protein that promotes gastric cancer progression through activating PI3K-Akt signaling
por: Zhang, Cheng, et al.
Publicado: (2020)

Selenoprotein M stimulates the proliferative and metastatic capacities of renal cell carcinoma through activating the PI3K/AKT/mTOR pathway
por: Jiang, Hao, et al.
Publicado: (2019)

The multidrug resistance can be reversed for the decrease of P-gp and LRP by inhibiting PI3K/Akt/NF-κB signal pathway in nasopharynx carcinoma
por: Liu, Jin, et al.
Publicado: (2020)

LncRNA UCA1 elevates the resistance of human leukemia cells to daunorubicin by the PI3K/AKT pathway via sponging miR-613
por: Yao, Qiying, et al.
Publicado: (2021)

Characterization, management, and risk factors of hyperglycemia during PI3K or AKT inhibitor treatment
por: Liu, Dazhi, et al.
Publicado: (2022)

RNF7 promotes glioma growth via the PI3K/AKT signalling axis
por: Tang, Nan, et al.
Publicado: (2022)

Apoptin‐derived peptide reverses cisplatin resistance in gastric cancer through the PI3K–AKT signaling pathway
por: Zhou, Danyang, et al.
Publicado: (2018)

Antitumor activity of celastrol by inhibition of proliferation, invasion, and migration in cholangiocarcinoma via PTEN/PI3K/Akt pathway
por: Zhu, Biqiang, et al.
Publicado: (2019)

PPA1 Promotes Breast Cancer Proliferation and Metastasis Through PI3K/AKT/GSK3β Signaling Pathway
por: Guo, Chunlei, et al.
Publicado: (2021)

TCONS_00012883 promotes proliferation and metastasis via DDX3/YY1/MMP1/PI3K‐AKT axis in colorectal cancer
por: Yang, Peng, et al.
Publicado: (2020)

Agmatinase promotes the lung adenocarcinoma tumorigenesis by activating the NO-MAPKs-PI3K/Akt pathway
por: Zhu, Hui-er, et al.
Publicado: (2019)

Synergistic interactions with PI3K inhibition that induce apoptosis
por: Zwang, Yaara, et al.
Publicado: (2017)

LncZEB1-AS1 regulates hepatocellular carcinoma bone metastasis via regulation of the miR-302b-EGFR-PI3K-AKT axis
por: Ma, Zhen-jiang, et al.
Publicado: (2020)

Targeting YAP‐p62 signaling axis suppresses the EGFR‐TKI‐resistant lung adenocarcinoma
por: Park, Hee Sun, et al.
Publicado: (2021)

JMJD8 Promotes Malignant Progression of Lung Cancer by Maintaining EGFR Stability and EGFR/PI3K/AKT Pathway Activation
por: Zhang, Bo, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_lj6ug15ra97n2sit4rq4ne1ufg