Cargando…

Antisense lncRNA LDLRAD4-AS1 promotes metastasis by decreasing the expression of LDLRAD4 and predicts a poor prognosis in colorectal cancer

Long noncoding RNAs (lncRNAs) have been revealed to play critical roles in tumor initiation and progression. The antisense lncRNA LDLRAD4-AS1 is the longest lncRNA of LDLRAD4, and its expression levels, cellular localization, precise function, and mechanism in colorectal cancer (CRC) remain unknown....

Descripción completa

Detalles Bibliográficos
Autores principales:	Mo, Shaobo, Zhang, Long, Dai, Weixing, Han, Lingyu, Wang, Renjie, Xiang, Wenqiang, Wang, Zhimin, Li, Qingguo, Yu, Jun, Yuan, Jihang, Cai, Sanjun, Cai, Guoxiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048743/ https://www.ncbi.nlm.nih.gov/pubmed/32111819 http://dx.doi.org/10.1038/s41419-020-2338-y

Ejemplares similares

LDLRAD3 is a receptor for Venezuelan equine encephalitis virus
por: Ma, Hongming, et al.
Publicado: (2020)

Structure of Venezuelan equine encephalitis virus in complex with the LDLRAD3 receptor
por: Basore, Katherine, et al.
Publicado: (2021)

Circular RNA circ-LDLRAD3 as a biomarker in diagnosis of pancreatic cancer
por: Yang, Fan, et al.
Publicado: (2017)

Development and external validation of a predictive scoring system associated with metastasis of T1‐2 colorectal tumors to lymph nodes
por: Mo, Shaobo, et al.
Publicado: (2020)

LDLRAD2 overexpression predicts poor prognosis and promotes metastasis by activating Wnt/β-catenin/EMT signaling cascade in gastric cancer
por: Wei, Yucai, et al.
Publicado: (2019)

CircLDLRAD3 inhibits Oral squamous cell carcinoma progression by regulating miR‐558/Smad4/TGF‐β
por: Zhang, Xue, et al.
Publicado: (2023)

Prognostic nomograms for predicting cause-specific survival and overall survival of stage I–III colon cancer patients: a large population-based study
por: Zhou, Zheng, et al.
Publicado: (2019)

Entry receptor LDLRAD3 is required for Venezuelan equine encephalitis virus peripheral infection and neurotropism leading to pathogenesis in mice
por: Kafai, Natasha M., et al.
Publicado: (2023)

PTPRO represses colorectal cancer tumorigenesis and progression by reprogramming fatty acid metabolism
por: Dai, Weixing, et al.
Publicado: (2022)

Development and Validation of an Autophagy Score Signature for the Prediction of Post-operative Survival in Colorectal Cancer
por: Zhou, Zheng, et al.
Publicado: (2019)

Ferroptosis-associated molecular classification characterized by distinct tumor microenvironment profiles in colorectal cancer
por: Luo, Wenqin, et al.
Publicado: (2022)

Comprehensive Transcriptomic Analysis Reveals Prognostic Value of an EMT-Related Gene Signature in Colorectal Cancer
por: Mo, Shaobo, et al.
Publicado: (2021)

Expression status of circ-SMARCA5, circ-NOL10, circ-LDLRAD3, and circ-RHOT1 in patients with colorectal cancer
por: Hussein, Neveen A., et al.
Publicado: (2023)

Prognostic and predictive value of radiomics signatures in stage I‐III colon cancer
por: Dai, Weixing, et al.
Publicado: (2020)

Enhanced glutamine utilization mediated by SLC1A5 and GPT2 is an essential metabolic feature of colorectal signet ring cell carcinoma with therapeutic potential
por: Wang, Renjie, et al.
Publicado: (2020)

GLUT3 induced by AMPK/CREB1 axis is key for withstanding energy stress and augments the efficacy of current colorectal cancer therapies
por: Dai, Weixing, et al.
Publicado: (2020)

FOXE1 represses cell proliferation and Warburg effect by inhibiting HK2 in colorectal cancer
por: Dai, Weixing, et al.
Publicado: (2020)

Changes in Incidence and Survival by Decade of Patients With Primary Colorectal Lymphoma: A SEER Analysis
por: Li, Qingguo, et al.
Publicado: (2020)

circ-LDLRAD3 Knockdown Reduces Cisplatin Chemoresistance and Inhibits the Development of Gastric Cancer with Cisplatin Resistance through miR-588 Enrichment-Mediated SOX5 Inhibition
por: Liang, Qianping, et al.
Publicado: (2023)

Enhanced De Novo Lipid Synthesis Mediated by FASN Induces Chemoresistance in Colorectal Cancer
por: Han, Lingyu, et al.
Publicado: (2023)

Fecal Multidimensional Assay for Non-Invasive Detection of Colorectal Cancer: Fecal Immunochemical Test, Stool DNA Mutation, Methylation, and Intestinal Bacteria Analysis
por: Mo, Shaobo, et al.
Publicado: (2021)

Survival Contradiction Between Stage IIA and Stage IIIA Rectal Cancer: A Retrospective Study
por: Mo, Shaobo, et al.
Publicado: (2018)

Low expression of novel lncRNA RP11-462C24.1 suggests a biomarker of poor prognosis in colorectal cancer
por: Shi, Debing, et al.
Publicado: (2014)

Hematopoietic Gene Expression Regulation Through m(6)A Methylation Predicts Prognosis in Stage III Colorectal Cancer
por: Zhou, Zheng, et al.
Publicado: (2020)

Bulk and single-cell transcriptome profiling reveal necroptosis-based molecular classification, tumor microenvironment infiltration characterization, and prognosis prediction in colorectal cancer
por: Luo, Wenqin, et al.
Publicado: (2022)

circRNA LDLRAD3 Enhances the Malignant Behaviors of NSCLC Cells via the miR-20a-5p-SLC7A5 Axis Activating the mTORC1 Signaling Pathway
por: Li, Yu, et al.
Publicado: (2022)

Retracted: circRNA LDLRAD3 Enhances the Malignant Behaviors of NSCLC Cells via the miR-20a-5p-SLC7A5 Axis Activating the mTORC1 Signaling Pathway
por: Healthcare Engineering, Journal of
Publicado: (2023)

Prognostic impact of programed cell death-1 (PD-1) and PD-ligand 1 (PD-L1) expression in cancer cells and tumor infiltrating lymphocytes in colorectal cancer
por: Li, Yaqi, et al.
Publicado: (2016)

Pathological nodal staging score for rectal cancer patients treated with radical surgery with or without neoadjuvant therapy: a postoperative decision tool
por: Dai, Weixing, et al.
Publicado: (2019)

Early detection and prognosis prediction for colorectal cancer by circulating tumour DNA methylation haplotypes: A multicentre cohort study
por: Mo, Shaobo, et al.
Publicado: (2022)

A robust gene signature for the prediction of early relapse in stage I–III colon cancer
por: Dai, Weixing, et al.
Publicado: (2018)

Solitary lymph node metastasis is a distinct subset of colon cancer associated with good survival: a retrospective study of surveillance, epidemiology, and end-results population-based data
por: Li, Qingguo, et al.
Publicado: (2014)

FBW7 suppresses metastasis of colorectal cancer by inhibiting HIF1α/CEACAM5 functional axis
por: Li, Qingguo, et al.
Publicado: (2018)

Modeling tumor development and metastasis using paired organoids derived from patients with colorectal cancer liver metastases
por: Li, He, et al.
Publicado: (2020)

LncRNA PVT1 Is a Poor Prognosticator and Can Be Targeted by PVT1 Antisense Oligos in Gastric Adenocarcinoma
por: Li, Yuan, et al.
Publicado: (2020)

miR-139-5p Inhibits the Epithelial-Mesenchymal Transition and Enhances the Chemotherapeutic Sensitivity of Colorectal Cancer Cells by Downregulating BCL2
por: Li, Qingguo, et al.
Publicado: (2016)

Expansion of antisense lncRNA transcriptomes since the loss of RNAi
por: Alcid, Eric A., et al.
Publicado: (2016)

Antisense lncRNA CHROMR is linked to glioma patient survival
por: Širvinskas, Dovydas, et al.
Publicado: (2023)

Better Long-Term Survival in Young Patients with Non-Metastatic Colorectal Cancer after Surgery, an Analysis of 69,835 Patients in SEER Database
por: Li, Qingguo, et al.
Publicado: (2014)

Identification of a KIR antisense lncRNA expressed by progenitor cells
por: Wright, Paul W., et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_fm0pil0jd9ukfm45kk4lg0nhp1