Mass spectrometry-based identification of a B-cell maturation antigen-derived T-cell epitope for antigen-specific immunotherapy of multiple myeloma

The B-cell maturation antigen (BCMA) is currently being evaluated as promising tumor-associated surface antigen for T-cell-based immunotherapy approaches, such as CAR T cells and bispecific antibodies, in multiple myeloma (MM). Cytotoxic T cells bearing BCMA-specific T-cell receptors might further a...

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Detalles Bibliográficos
Autores principales: Bilich, Tatjana, Nelde, Annika, Bauer, Jens, Walz, Simon, Roerden, Malte, Salih, Helmut R., Weisel, Katja, Besemer, Britta, Marcu, Ana, Lübke, Maren, Schuhmacher, Juliane, Neidert, Marian C., Rammensee, Hans-Georg, Stevanović, Stefan, Walz, Juliane S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048774/
https://www.ncbi.nlm.nih.gov/pubmed/32111817
http://dx.doi.org/10.1038/s41408-020-0288-3

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