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MCL1 binding to the reverse BH3 motif of P18INK4C couples cell survival to cell proliferation
Commitment to cell cycle entry and cellular duplication is a tightly coordinated and regulated process. Once initiated, a series of multiple checkpoints ensure both accurate genomic replication and chromosomal separation. In the event of unsuccessful cell division, parallel pathways exist that induc...
Autores principales: | Whitaker, Robert H., Placzek, William J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048787/ https://www.ncbi.nlm.nih.gov/pubmed/32111816 http://dx.doi.org/10.1038/s41419-020-2351-1 |
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