A CRISPR-Cas9-based reporter system for single-cell detection of extracellular vesicle-mediated functional transfer of RNA

Extracellular vesicles (EVs) form an endogenous transport system for intercellular transfer of biological cargo, including RNA, that plays a pivotal role in physiological and pathological processes. Unfortunately, whereas biological effects of EV-mediated RNA transfer are abundantly studied, regulat...

Descripción completa

Detalles Bibliográficos
Autores principales: de Jong, Olivier G., Murphy, Daniel E., Mäger, Imre, Willms, Eduard, Garcia-Guerra, Antonio, Gitz-Francois, Jerney J., Lefferts, Juliet, Gupta, Dhanu, Steenbeek, Sander C., van Rheenen, Jacco, El Andaloussi, Samir, Schiffelers, Raymond M., Wood, Matthew J. A., Vader, Pieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048928/
https://www.ncbi.nlm.nih.gov/pubmed/32111843
http://dx.doi.org/10.1038/s41467-020-14977-8

Ejemplares similares

Ejemplares similares