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Structural analysis of a trimeric assembly of the mitochondrial dynamin-like GTPase Mgm1
The fusion of inner mitochondrial membranes requires dynamin-like GTPases, Mgm1 in yeast and OPA1 in mammals, but how they mediate membrane fusion is poorly understood. Here, we determined the crystal structure of Saccharomyces cerevisiae short Mgm1 (s-Mgm1) in complex with GDP. It revealed an N-ter...
Autores principales: | Yan, Liming, Qi, Yuanbo, Ricketson, Derek, Li, Lei, Subramanian, Kelly, Zhao, Jinghua, Yu, Caiting, Wu, Lijie, Sarsam, Reta, Wong, Melissa, Lou, Zhiyong, Rao, Zihe, Nunnari, Jodi, Hu, Junjie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049166/ https://www.ncbi.nlm.nih.gov/pubmed/32041880 http://dx.doi.org/10.1073/pnas.1919116117 |
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