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A reference profile-free deconvolution method to infer cancer cell-intrinsic subtypes and tumor-type-specific stromal profiles

BACKGROUND: Patient stratification based on molecular subtypes is an important strategy for cancer precision medicine. Deriving clinically informative cancer molecular subtypes from transcriptomic data generated on whole tumor tissue samples is a non-trivial task, especially given the various non-ca...

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Detalles Bibliográficos
Autores principales:	Wang, Li, Sebra, Robert P., Sfakianos, John P., Allette, Kimaada, Wang, Wenhui, Yoo, Seungyeul, Bhardwaj, Nina, Schadt, Eric E., Yao, Xin, Galsky, Matthew D., Zhu, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049190/ https://www.ncbi.nlm.nih.gov/pubmed/32111252 http://dx.doi.org/10.1186/s13073-020-0720-0

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