Effect of intraocular anti-VEGF on cystoid macular edema associated with Henoch-Schonlein purpura-a case report

BACKGROUND: To report a bilateral cystoid macular edema associated with Henoch-Schonleinpurpura. CASE PRESENTATION: A 21-year-old man presented a bilateral, painless, and bilateral blurred vision for 5 weeks with visual acuity (VA) of 6/12 on the right eye and 6/48 on the left. FA and OCT showed bil...

Descripción completa

Detalles Bibliográficos
Autores principales: Pan, Dongyan, Cui, Xiao, Zhu, Weiye, Qin, Haifeng, Li, Qing, Xu, Bing, Wu, Jin-hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049220/
https://www.ncbi.nlm.nih.gov/pubmed/32111177
http://dx.doi.org/10.1186/s12886-020-01351-x
_version_ 1783502396166504448
author Pan, Dongyan
Cui, Xiao
Zhu, Weiye
Qin, Haifeng
Li, Qing
Xu, Bing
Wu, Jin-hui
author_facet Pan, Dongyan
Cui, Xiao
Zhu, Weiye
Qin, Haifeng
Li, Qing
Xu, Bing
Wu, Jin-hui
author_sort Pan, Dongyan
collection PubMed
description BACKGROUND: To report a bilateral cystoid macular edema associated with Henoch-Schonleinpurpura. CASE PRESENTATION: A 21-year-old man presented a bilateral, painless, and bilateral blurred vision for 5 weeks with visual acuity (VA) of 6/12 on the right eye and 6/48 on the left. FA and OCT showed bilateral cystoid macular edema, and the fundus photograph showed retinal hemorrhages. Using intravenous dexamethasone could reduce macular edema, but it reoccurred shortly after switching to oral prednisone. Repeated intraocular injection of anti-VEGF in both eyes was performed and VA improved to 6/6 on the right eye and 6/7.5 on the left with the regression of edema after 6 months follow-up. CONCLUSIONS: Intraocular anti-VEGF might be an alternative choice to glucocorticoid in cases of bilateral cystoid macular edema associated with Henoch-Schonlein purpura.
format Online
Article
Text
id pubmed-7049220
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-70492202020-03-05 Effect of intraocular anti-VEGF on cystoid macular edema associated with Henoch-Schonlein purpura-a case report Pan, Dongyan Cui, Xiao Zhu, Weiye Qin, Haifeng Li, Qing Xu, Bing Wu, Jin-hui BMC Ophthalmol Case Report BACKGROUND: To report a bilateral cystoid macular edema associated with Henoch-Schonleinpurpura. CASE PRESENTATION: A 21-year-old man presented a bilateral, painless, and bilateral blurred vision for 5 weeks with visual acuity (VA) of 6/12 on the right eye and 6/48 on the left. FA and OCT showed bilateral cystoid macular edema, and the fundus photograph showed retinal hemorrhages. Using intravenous dexamethasone could reduce macular edema, but it reoccurred shortly after switching to oral prednisone. Repeated intraocular injection of anti-VEGF in both eyes was performed and VA improved to 6/6 on the right eye and 6/7.5 on the left with the regression of edema after 6 months follow-up. CONCLUSIONS: Intraocular anti-VEGF might be an alternative choice to glucocorticoid in cases of bilateral cystoid macular edema associated with Henoch-Schonlein purpura. BioMed Central 2020-02-28 /pmc/articles/PMC7049220/ /pubmed/32111177 http://dx.doi.org/10.1186/s12886-020-01351-x Text en © The Author(s) 2020 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Pan, Dongyan
Cui, Xiao
Zhu, Weiye
Qin, Haifeng
Li, Qing
Xu, Bing
Wu, Jin-hui
Effect of intraocular anti-VEGF on cystoid macular edema associated with Henoch-Schonlein purpura-a case report
title Effect of intraocular anti-VEGF on cystoid macular edema associated with Henoch-Schonlein purpura-a case report
title_full Effect of intraocular anti-VEGF on cystoid macular edema associated with Henoch-Schonlein purpura-a case report
title_fullStr Effect of intraocular anti-VEGF on cystoid macular edema associated with Henoch-Schonlein purpura-a case report
title_full_unstemmed Effect of intraocular anti-VEGF on cystoid macular edema associated with Henoch-Schonlein purpura-a case report
title_short Effect of intraocular anti-VEGF on cystoid macular edema associated with Henoch-Schonlein purpura-a case report
title_sort effect of intraocular anti-vegf on cystoid macular edema associated with henoch-schonlein purpura-a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049220/
https://www.ncbi.nlm.nih.gov/pubmed/32111177
http://dx.doi.org/10.1186/s12886-020-01351-x
work_keys_str_mv AT pandongyan effectofintraocularantivegfoncystoidmacularedemaassociatedwithhenochschonleinpurpuraacasereport
AT cuixiao effectofintraocularantivegfoncystoidmacularedemaassociatedwithhenochschonleinpurpuraacasereport
AT zhuweiye effectofintraocularantivegfoncystoidmacularedemaassociatedwithhenochschonleinpurpuraacasereport
AT qinhaifeng effectofintraocularantivegfoncystoidmacularedemaassociatedwithhenochschonleinpurpuraacasereport
AT liqing effectofintraocularantivegfoncystoidmacularedemaassociatedwithhenochschonleinpurpuraacasereport
AT xubing effectofintraocularantivegfoncystoidmacularedemaassociatedwithhenochschonleinpurpuraacasereport
AT wujinhui effectofintraocularantivegfoncystoidmacularedemaassociatedwithhenochschonleinpurpuraacasereport

Ejemplares similares