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Additional Diagnostic Value of Unenhanced Computed Tomography plus Diffusion-Weighted Imaging Combined with Routine Magnetic Resonance Imaging Findings of Early-Stage Gliblastoma

PURPOSE: This study was performed to determine whether diffusion-weighted imaging (DWI) plus unenhanced computed tomography (CT) of the brain increases the diagnostic value of routine magnetic resonance (MR) imaging findings of early-stage glioblastoma. METHODS: Postcontrast MR images of eight unenh...

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Autores principales: Wang, Hexiang, Liu, Zhenyou, Zhang, Yong, Hou, Feng, Fu, Weiwei, Lin, Jizheng, Liu, Yingchao, Liu, Xuejun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049329/
https://www.ncbi.nlm.nih.gov/pubmed/32149081
http://dx.doi.org/10.1155/2020/1672736
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author Wang, Hexiang
Liu, Zhenyou
Zhang, Yong
Hou, Feng
Fu, Weiwei
Lin, Jizheng
Liu, Yingchao
Liu, Xuejun
author_facet Wang, Hexiang
Liu, Zhenyou
Zhang, Yong
Hou, Feng
Fu, Weiwei
Lin, Jizheng
Liu, Yingchao
Liu, Xuejun
author_sort Wang, Hexiang
collection PubMed
description PURPOSE: This study was performed to determine whether diffusion-weighted imaging (DWI) plus unenhanced computed tomography (CT) of the brain increases the diagnostic value of routine magnetic resonance (MR) imaging findings of early-stage glioblastoma. METHODS: Postcontrast MR images of eight unenhanced lesions that had been pathologically diagnosed as glioblastoma were retrospectively examined. The location, margin, signal intensity, and attenuation on MR imaging and CT were assessed. RESULTS: On MR imaging, all lesions were ill-defined, small, and isointense to hypointense on T1-weighted images and hyperintense on T2-weighted images. Four patients had perilesional edema. In seven patients, DWI showed an inhomogeneous hyperintense lesion (n = 1) or isointense lesion with a hyperintense region (n = 1) or isointense lesion with a hyperintense region (n = 1) or isointense lesion with a hyperintense region (n = 1) or isointense lesion with a hyperintense region (n = 1) or isointense lesion with a hyperintense region (n = 1) or isointense lesion with a hyperintense region (n = 1) or isointense lesion with a hyperintense region (n = 1) or isointense lesion with a hyperintense region (n = 1) or isointense lesion with a hyperintense region ( CONCLUSIONS: MR imaging was the most sensitive imaging method for depicting early-stage glioblastoma. The CT finding of a hyperattenuated or isoattenuated region combined with the DWI finding of the same region containing an inhomogeneous hyperintense lesion or isointense lesion with a hyperintense region may be a specific diagnostic sign for early-stage glioblastoma. DWI plus unenhanced CT added diagnostic value to the routine MR imaging findings of early-stage glioblastoma.
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spelling pubmed-70493292020-03-08 Additional Diagnostic Value of Unenhanced Computed Tomography plus Diffusion-Weighted Imaging Combined with Routine Magnetic Resonance Imaging Findings of Early-Stage Gliblastoma Wang, Hexiang Liu, Zhenyou Zhang, Yong Hou, Feng Fu, Weiwei Lin, Jizheng Liu, Yingchao Liu, Xuejun Biomed Res Int Research Article PURPOSE: This study was performed to determine whether diffusion-weighted imaging (DWI) plus unenhanced computed tomography (CT) of the brain increases the diagnostic value of routine magnetic resonance (MR) imaging findings of early-stage glioblastoma. METHODS: Postcontrast MR images of eight unenhanced lesions that had been pathologically diagnosed as glioblastoma were retrospectively examined. The location, margin, signal intensity, and attenuation on MR imaging and CT were assessed. RESULTS: On MR imaging, all lesions were ill-defined, small, and isointense to hypointense on T1-weighted images and hyperintense on T2-weighted images. Four patients had perilesional edema. In seven patients, DWI showed an inhomogeneous hyperintense lesion (n = 1) or isointense lesion with a hyperintense region (n = 1) or isointense lesion with a hyperintense region (n = 1) or isointense lesion with a hyperintense region (n = 1) or isointense lesion with a hyperintense region (n = 1) or isointense lesion with a hyperintense region (n = 1) or isointense lesion with a hyperintense region (n = 1) or isointense lesion with a hyperintense region (n = 1) or isointense lesion with a hyperintense region (n = 1) or isointense lesion with a hyperintense region ( CONCLUSIONS: MR imaging was the most sensitive imaging method for depicting early-stage glioblastoma. The CT finding of a hyperattenuated or isoattenuated region combined with the DWI finding of the same region containing an inhomogeneous hyperintense lesion or isointense lesion with a hyperintense region may be a specific diagnostic sign for early-stage glioblastoma. DWI plus unenhanced CT added diagnostic value to the routine MR imaging findings of early-stage glioblastoma. Hindawi 2020-02-18 /pmc/articles/PMC7049329/ /pubmed/32149081 http://dx.doi.org/10.1155/2020/1672736 Text en Copyright © 2020 Hexiang Wang et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Wang, Hexiang
Liu, Zhenyou
Zhang, Yong
Hou, Feng
Fu, Weiwei
Lin, Jizheng
Liu, Yingchao
Liu, Xuejun
Additional Diagnostic Value of Unenhanced Computed Tomography plus Diffusion-Weighted Imaging Combined with Routine Magnetic Resonance Imaging Findings of Early-Stage Gliblastoma
title Additional Diagnostic Value of Unenhanced Computed Tomography plus Diffusion-Weighted Imaging Combined with Routine Magnetic Resonance Imaging Findings of Early-Stage Gliblastoma
title_full Additional Diagnostic Value of Unenhanced Computed Tomography plus Diffusion-Weighted Imaging Combined with Routine Magnetic Resonance Imaging Findings of Early-Stage Gliblastoma
title_fullStr Additional Diagnostic Value of Unenhanced Computed Tomography plus Diffusion-Weighted Imaging Combined with Routine Magnetic Resonance Imaging Findings of Early-Stage Gliblastoma
title_full_unstemmed Additional Diagnostic Value of Unenhanced Computed Tomography plus Diffusion-Weighted Imaging Combined with Routine Magnetic Resonance Imaging Findings of Early-Stage Gliblastoma
title_short Additional Diagnostic Value of Unenhanced Computed Tomography plus Diffusion-Weighted Imaging Combined with Routine Magnetic Resonance Imaging Findings of Early-Stage Gliblastoma
title_sort additional diagnostic value of unenhanced computed tomography plus diffusion-weighted imaging combined with routine magnetic resonance imaging findings of early-stage gliblastoma
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049329/
https://www.ncbi.nlm.nih.gov/pubmed/32149081
http://dx.doi.org/10.1155/2020/1672736
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