Multilevel defects in the hematopoietic niche in essential thrombocythemia

The role of the bone marrow niche in essential thrombocythemia (ET) remains unclear. Here, we observed multilevel defects in the hematopoietic niche of patients with JAK2V617F-positive ET, including functional deficiency in mesenchymal stromal cells (MSC), immune imbalance, and sympathetic-nerve dam...

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Detalles Bibliográficos
Autores principales: Sun, Ting, Ju, Mankai, Dai, Xinyue, Dong, Huan, Gu, Wenjing, Gao, Yuchen, Fu, Rongfeng, Liu, Xiaofan, Huang, Yueting, Liu, Wei, Ch, Ying, Wang, Wentian, Li, Huiyuan, Zhou, Yuan, Shi, Lihong, Yang, Renchi, Zhang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049349/
https://www.ncbi.nlm.nih.gov/pubmed/31289202
http://dx.doi.org/10.3324/haematol.2018.213686

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