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The hydroxymethylome of multiple myeloma identifies FAM72D as a 1q21 marker linked to proliferation
Cell identity relies on the cross-talk between genetics and epigenetics and their impact on gene expression. Oxidation of 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) is the first step of an active DNA demethylation process occurring mainly at enhancers and gene bodies and, as such, pa...
Autores principales: | Chatonnet, Fabrice, Pignarre, Amandine, Sérandour, Aurélien A., Caron, Gersende, Avner, Stéphane, Robert, Nicolas, Kassambara, Alboukadel, Laurent, Audrey, Bizot, Maud, Agirre, Xabier, Prosper, Felipe, Martin-Subero, José I., Moreaux, Jérôme, Fest, Thierry, Salbert, Gilles |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ferrata Storti Foundation
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049362/ https://www.ncbi.nlm.nih.gov/pubmed/31221779 http://dx.doi.org/10.3324/haematol.2019.222133 |
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