Cargando…

Combination of dextromethorphan and memantine in treating bipolar spectrum disorder: a 12-week double-blind randomized clinical trial

BACKGROUND: The aim of this study is to determine whether adding combination of agents with anti-inflammatory and neurotrophic effects is more efficacious than mood stabilizer alone in improving clinical symptoms, plasma brain-derived neurotrophic factor (BDNF), cytokine levels, and metabolic profil...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lee, Sheng-Yu, Wang, Tzu-Yun, Chen, Shiou-Lan, Chang, Yun-Hsuan, Chen, Po-See, Huang, San-Yuan, Tzeng, Nian-Sheng, Wang, Liang-Jen, Lee, I-Hui, Chen, Kao-Ching, Yang, Yen-Kuang, Hong, Jau-Shyong, Lu, Ru-Band
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049537/ https://www.ncbi.nlm.nih.gov/pubmed/32115672 http://dx.doi.org/10.1186/s40345-019-0174-8

Ejemplares similares

Dextromethorphan Protect the Valproic Acid Induced Downregulation of Neutrophils in Patients with Bipolar Disorder
por: Lu, Ru-Band, et al.
Publicado: (2020)

Low-dose memantine attenuated methadone dose in opioid-dependent patients: a 12-week double-blind randomized controlled trial
por: Lee, Sheng-Yu, et al.
Publicado: (2015)

A Placebo-Controlled Trial of Dextromethorphan as an Adjunct in Opioid-Dependent Patients Undergoing Methadone Maintenance Treatment
por: Lee, Sheng-Yu, et al.
Publicado: (2015)

Low-dose add-on memantine treatment may improve cognitive performance and self-reported health conditions in opioid-dependent patients undergoing methadone-maintenance-therapy
por: Chang, Yun-Hsuan, et al.
Publicado: (2015)

Corrigendum: Low-dose add-on memantine treatment may improve cognitive performance and self-reported health conditions in opioid-dependent patients undergoing methadone-maintenance-therapy
por: Chang, Yun-Hsuan, et al.
Publicado: (2017)

Inflammation’s Association with Metabolic Profiles before and after a Twelve-Week Clinical Trial in Drug-Naïve Patients with Bipolar II Disorder
por: Lee, Sheng-Yu, et al.
Publicado: (2013)

Memory Impairment and Plasma BDNF Correlates of the BDNF Val66Met Polymorphism in Patients With Bipolar II Disorder
por: Chang, Yun-Hsuan, et al.
Publicado: (2018)

Comparing clinical responses and the biomarkers of BDNF and cytokines between subthreshold bipolar disorder and bipolar II disorder
por: Wang, Tzu-Yun, et al.
Publicado: (2016)

A potential interaction between COMT and MTHFR genetic variants in Han Chinese patients with bipolar II disorder
por: Wang, Liang-Jen, et al.
Publicado: (2015)

The Differential Levels of Inflammatory Cytokines and BDNF among Bipolar Spectrum Disorders
por: Wang, Tzu-Yun, et al.
Publicado: (2016)

The correlation between plasma brain-derived neurotrophic factor and cognitive function in bipolar disorder is modulated by the BDNF Val66Met polymorphism
por: Lee, Sheng-Yu, et al.
Publicado: (2016)

The DRD3 Ser9Gly Polymorphism Predicted Metabolic Change in Drug-Naive Patients With Bipolar II Disorder
por: Chang, Ting-Ting, et al.
Publicado: (2016)

ALDH2 Gene: Its Effects on the Neuropsychological Functions in Patients with Opioid Use Disorder Undergoing Methadone Maintenance Treatment
por: Lee, Po-Wei, et al.
Publicado: (2020)

Association Between Inflammatory Cytokines, Executive Function, and Substance Use in Patients With Opioid Use Disorder and Amphetamine-Type Stimulants Use Disorder
por: Wang, Tzu-Yun, et al.
Publicado: (2022)

Effects of mood episodes and comorbid anxiety on neuropsychological impairment in patients with bipolar spectrum disorder
por: Huang, Chih‐Chun, et al.
Publicado: (2020)

The BDNF Val66Met polymorphism and plasma brain-derived neurotrophic factor levels in Han Chinese heroin-dependent patients
por: Chen, Shiou-Lan, et al.
Publicado: (2015)

The aldehyde dehydrogenase 2 polymorphisms on neuropsychological performance in bipolar II disorder with or without comorbid anxiety disorder
por: Lu, Ru-Band, et al.
Publicado: (2018)

Dextromethorphan Inhibits Activations and Functions in Dendritic Cells
por: Chen, Der-Yuan, et al.
Publicado: (2013)

Dextromethorphan and memantine after ketamine analgesia: a randomized control trial
por: Martin, Elodie, et al.
Publicado: (2019)

Impairment in Emotional Intelligence May Be Mood-Dependent in Bipolar I and Bipolar II Disorders
por: Kuo, Shih-Yu, et al.
Publicado: (2021)

Poorer sustained attention in bipolar I than bipolar II disorder
por: Kung, Chian-Huei, et al.
Publicado: (2010)

Interaction between Serotonin Transporter and Serotonin Receptor 1 B genes polymorphisms may be associated with antisocial alcoholism
por: Wang, Tzu-Yun, et al.
Publicado: (2012)

A Study of Potential Pharmacokinetic and Pharmacodynamic Interactions between Dextromethorphan/Quinidine and Memantine in Healthy Volunteers
por: Pope, Laura E., et al.
Publicado: (2012)

Potential Negative Effects of Dextromethorphan as an Add-On Therapy to Methylphenidate in Children With ADHD
por: Chuang, Wei-Chen, et al.
Publicado: (2019)

FGF21 Is Associated with Metabolic Effects and Treatment Response in Depressed Bipolar II Disorder Patients Treated with Valproate
por: Chang, Hui Hua, et al.
Publicado: (2017)

Dextromethorphan Reduces Oxidative Stress and Inhibits Uremic Artery Calcification
por: Liu, En-Shao, et al.
Publicado: (2021)

Serum miRNA as a possible biomarker in the diagnosis of bipolar II disorder
por: Lee, Sheng-Yu, et al.
Publicado: (2020)

PS50. The serum oxytocin levels among major depressive and bipolar II disorder
por: Lien, Yueh-Ju, et al.
Publicado: (2016)

Memantine in the management of a clinically challenging case of bipolar disorder
por: Agarwal, Vivek, et al.
Publicado: (2009)

Plasma BDNF and Cytokines Correlated with Protein Biomarkers for Bipolar II Disorder
por: Lee, Sheng-Yu, et al.
Publicado: (2021)

Dextromethorphan Suppresses Lipopolysaccharide-Induced Epigenetic Histone Regulation in the Tumor Necrosis Factor-α Expression in Primary Rat Microglia
por: Yang, Yung-Ning, et al.
Publicado: (2020)

A 10-Week Memantine Treatment in Bipolar Depression: A Case Report. Focus on Depressive Symptomatology, Cognitive Parameters and Quality of Life
por: Strzelecki, Dominik, et al.
Publicado: (2013)

Identifying Potential Regions of Copy Number Variation for Bipolar Disorder
por: Chen, Yi-Hsuan, et al.
Publicado: (2014)

Dextromethorphan Exhibits Anti-Inflammatory and Immunomodulatory Effects in a Murine Model: Therapeutic Implication in Psoriasis
por: Chen, Yi-Ming, et al.
Publicado: (2022)

Identification of potential plasma protein biomarkers for bipolar II disorder: a preliminary/exploratory study
por: Lee, Sheng-Yu, et al.
Publicado: (2021)

Cognitive performance in older elderly men with late-life depression and cardiovascular comorbidities: symptomatological correlation
por: Chang, Yun-Hsuan, et al.
Publicado: (2013)

The correlation between longitudinal changes in hypothalamic–pituitary–adrenal (HPA)-axis activity and changes in neurocognitive function in mixed-state bipolar II disorder
por: Lee, Hsuan-Han, et al.
Publicado: (2018)

Deuterated dextromethorphan/quinidine for agitation in Alzheimer's disease
por: Khoury, Rita
Publicado: (2021)

Antipsychotic Drugs Efficacy in Dextromethorphan-Induced Psychosis
por: Zaremba, Malgorzata, et al.
Publicado: (2023)

Bilateral nephrolithiasis following ingestion of guaifenesin and dextromethorphan
por: Kim, Elizabeth, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_qk0r2ejou6aq63guir3orfl62p