Repurposing antimycotic ciclopirox olamine as a promising anti-ischemic stroke agent

Ischemic stroke is a severe disorder resulting from acute cerebral thrombosis. Here we demonstrated that post-ischemic treatment with ciclopirox olamine (CPX), a potent antifungal clinical drug, alleviated brain infarction, neurological deficits and brain edema in a classic rat model of ischemic str...

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Detalles Bibliográficos
Autores principales: Feng, Hongxuan, Hu, Linghao, Zhu, Hongwen, Tao, Lingxue, Wu, Lei, Zhao, Qinyuan, Gao, Yemi, Gong, Qi, Mao, Fei, Li, Xiaokang, Zhou, Hu, Li, Jian, Zhang, Haiyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049605/
https://www.ncbi.nlm.nih.gov/pubmed/32140390
http://dx.doi.org/10.1016/j.apsb.2019.08.002

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