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Primary Tuberculous Mastitis: The first report from Syria

INTRODUCTION: Primary breast tuberculosis is a rare form of extrapulmonary tuberculosis even in endemic regions. To our knowledge, this is the first report of Primary breast tuberculosis from Syria. CASE PRESENTATION: We report a case of a 37-year-old female who admitted to the surgical clinic with...

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Autores principales: Kayali, Sadallah, Alhamid, Aos, Kayali, Ayman, Danial, Aghyad Kudra, Brimo Alsaman, Muhamad Zakaria, Alhamid, Ahmad, Ayoub, Kusay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049629/
https://www.ncbi.nlm.nih.gov/pubmed/32114352
http://dx.doi.org/10.1016/j.ijscr.2020.02.007
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author Kayali, Sadallah
Alhamid, Aos
Kayali, Ayman
Danial, Aghyad Kudra
Brimo Alsaman, Muhamad Zakaria
Alhamid, Ahmad
Ayoub, Kusay
author_facet Kayali, Sadallah
Alhamid, Aos
Kayali, Ayman
Danial, Aghyad Kudra
Brimo Alsaman, Muhamad Zakaria
Alhamid, Ahmad
Ayoub, Kusay
author_sort Kayali, Sadallah
collection PubMed
description INTRODUCTION: Primary breast tuberculosis is a rare form of extrapulmonary tuberculosis even in endemic regions. To our knowledge, this is the first report of Primary breast tuberculosis from Syria. CASE PRESENTATION: We report a case of a 37-year-old female who admitted to the surgical clinic with a 4-month history of gradually growing mass in the breast. On physical examination there were a palpable mass, painful superficial abscess in her left lateral upper quarter of breast, redness and nipple retraction and ulceration. The patient history and physical examination were clear except for uncontrolled hypothyroidism. Radiological tests including mammography, echography and laboratory investigations were performed. The patient underwent lumpectomy. Histopathologic examination showed caseating Tuberculous Mastitis and a large tuberculous abscess, with no malignancy. Patient was put on anti-tubercular chemotherapy, but recurred after three months with three masses in the same area because she did not adhere to the treatment. Lumpectomy and Anti-tuberculous therapy were repeated again with close follow-up, and the patient recovered. DISCUSSION: Primary breast tuberculosis forms about 0.025-0.1 % of all surgically treated breast diseases. Diagnosis is based on bacteriological and histological examination. We can get higher accuracy in diagnosis by biopsy such as a core needle or surgical biopsy, surgical biopsy is necessary to confirm the diagnosis of tuberculous mastitis. CONCLUSION: Tuberculous mastitis is extremely rare variant of extrapulmonary tuberculosis. However, it should be kept in the mind of physicians and pathologists while approaching a breast mass, especially in endemic area.
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spelling pubmed-70496292020-03-05 Primary Tuberculous Mastitis: The first report from Syria Kayali, Sadallah Alhamid, Aos Kayali, Ayman Danial, Aghyad Kudra Brimo Alsaman, Muhamad Zakaria Alhamid, Ahmad Ayoub, Kusay Int J Surg Case Rep Article INTRODUCTION: Primary breast tuberculosis is a rare form of extrapulmonary tuberculosis even in endemic regions. To our knowledge, this is the first report of Primary breast tuberculosis from Syria. CASE PRESENTATION: We report a case of a 37-year-old female who admitted to the surgical clinic with a 4-month history of gradually growing mass in the breast. On physical examination there were a palpable mass, painful superficial abscess in her left lateral upper quarter of breast, redness and nipple retraction and ulceration. The patient history and physical examination were clear except for uncontrolled hypothyroidism. Radiological tests including mammography, echography and laboratory investigations were performed. The patient underwent lumpectomy. Histopathologic examination showed caseating Tuberculous Mastitis and a large tuberculous abscess, with no malignancy. Patient was put on anti-tubercular chemotherapy, but recurred after three months with three masses in the same area because she did not adhere to the treatment. Lumpectomy and Anti-tuberculous therapy were repeated again with close follow-up, and the patient recovered. DISCUSSION: Primary breast tuberculosis forms about 0.025-0.1 % of all surgically treated breast diseases. Diagnosis is based on bacteriological and histological examination. We can get higher accuracy in diagnosis by biopsy such as a core needle or surgical biopsy, surgical biopsy is necessary to confirm the diagnosis of tuberculous mastitis. CONCLUSION: Tuberculous mastitis is extremely rare variant of extrapulmonary tuberculosis. However, it should be kept in the mind of physicians and pathologists while approaching a breast mass, especially in endemic area. Elsevier 2020-02-06 /pmc/articles/PMC7049629/ /pubmed/32114352 http://dx.doi.org/10.1016/j.ijscr.2020.02.007 Text en © 2020 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Kayali, Sadallah
Alhamid, Aos
Kayali, Ayman
Danial, Aghyad Kudra
Brimo Alsaman, Muhamad Zakaria
Alhamid, Ahmad
Ayoub, Kusay
Primary Tuberculous Mastitis: The first report from Syria
title Primary Tuberculous Mastitis: The first report from Syria
title_full Primary Tuberculous Mastitis: The first report from Syria
title_fullStr Primary Tuberculous Mastitis: The first report from Syria
title_full_unstemmed Primary Tuberculous Mastitis: The first report from Syria
title_short Primary Tuberculous Mastitis: The first report from Syria
title_sort primary tuberculous mastitis: the first report from syria
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049629/
https://www.ncbi.nlm.nih.gov/pubmed/32114352
http://dx.doi.org/10.1016/j.ijscr.2020.02.007
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