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Hepatocellular Carcinoma—How to Determine Therapeutic Options

Deciding on specific treatment strategies involves not only tumor stage, performance status, and severity of underlying liver disease, but additional factors such as biomarkers, organ availability, and radiographic tumor response to treatment. In this review, we present hepatocellular carcinoma (HCC...

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Detalles Bibliográficos
Autor principal: Mehta, Neil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049673/
https://www.ncbi.nlm.nih.gov/pubmed/32140653
http://dx.doi.org/10.1002/hep4.1481
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author Mehta, Neil
author_facet Mehta, Neil
author_sort Mehta, Neil
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description Deciding on specific treatment strategies involves not only tumor stage, performance status, and severity of underlying liver disease, but additional factors such as biomarkers, organ availability, and radiographic tumor response to treatment. In this review, we present hepatocellular carcinoma (HCC) cases to highlight how to determine therapeutic options for HCC in specific scenarios, including resection versus liver transplant, choice of initial local regional treatment, tumor downstaging, and systemic therapies for advanced HCC.
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spelling pubmed-70496732020-03-05 Hepatocellular Carcinoma—How to Determine Therapeutic Options Mehta, Neil Hepatol Commun Reviews Deciding on specific treatment strategies involves not only tumor stage, performance status, and severity of underlying liver disease, but additional factors such as biomarkers, organ availability, and radiographic tumor response to treatment. In this review, we present hepatocellular carcinoma (HCC) cases to highlight how to determine therapeutic options for HCC in specific scenarios, including resection versus liver transplant, choice of initial local regional treatment, tumor downstaging, and systemic therapies for advanced HCC. John Wiley and Sons Inc. 2020-01-22 /pmc/articles/PMC7049673/ /pubmed/32140653 http://dx.doi.org/10.1002/hep4.1481 Text en © 2020 The Authors. Hepatology Communications published by Wiley Periodicals, Inc., on behalf of the American Association for the Study of Liver Diseases. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Reviews
Mehta, Neil
Hepatocellular Carcinoma—How to Determine Therapeutic Options
title Hepatocellular Carcinoma—How to Determine Therapeutic Options
title_full Hepatocellular Carcinoma—How to Determine Therapeutic Options
title_fullStr Hepatocellular Carcinoma—How to Determine Therapeutic Options
title_full_unstemmed Hepatocellular Carcinoma—How to Determine Therapeutic Options
title_short Hepatocellular Carcinoma—How to Determine Therapeutic Options
title_sort hepatocellular carcinoma—how to determine therapeutic options
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049673/
https://www.ncbi.nlm.nih.gov/pubmed/32140653
http://dx.doi.org/10.1002/hep4.1481
work_keys_str_mv AT mehtaneil hepatocellularcarcinomahowtodeterminetherapeuticoptions