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HSF2BP negatively regulates homologous recombination in DNA interstrand crosslink repair
The tumor suppressor BRCA2 is essential for homologous recombination (HR), replication fork stability and DNA interstrand crosslink (ICL) repair in vertebrates. We show that ectopic production of HSF2BP, a BRCA2-interacting protein required for meiotic HR during mouse spermatogenesis, in non-germlin...
Autores principales: | Sato, Koichi, Brandsma, Inger, van Rossum-Fikkert, Sari E, Verkaik, Nicole, Oostra, Anneke B, Dorsman, Josephine C, van Gent, Dik C, Knipscheer, Puck, Kanaar, Roland, Zelensky, Alex N |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049687/ https://www.ncbi.nlm.nih.gov/pubmed/31960047 http://dx.doi.org/10.1093/nar/gkz1219 |
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