Enhancer–gene maps in the human and zebrafish genomes using evolutionary linkage conservation

The spatiotemporal expression of genes is controlled by enhancer sequences that bind transcription factors. Identifying the target genes of enhancers remains difficult because enhancers regulate gene expression over long genomic distances. To address this, we used an evolutionary approach to build t...

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Detalles Bibliográficos
Autores principales: Clément, Yves, Torbey, Patrick, Gilardi-Hebenstreit, Pascale, Crollius, Hugues Roest
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049698/
https://www.ncbi.nlm.nih.gov/pubmed/31943068
http://dx.doi.org/10.1093/nar/gkz1199

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049698/
https://www.ncbi.nlm.nih.gov/pubmed/31943068
http://dx.doi.org/10.1093/nar/gkz1199

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