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BHi-Cect: a top-down algorithm for identifying the multi-scale hierarchical structure of chromosomes
High-throughput chromosome conformation capture (Hi-C) technology enables the investigation of genome-wide interactions among chromosome loci. Current algorithms focus on topologically associating domains (TADs), that are contiguous clusters along the genome coordinate, to describe the hierarchical...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049727/ https://www.ncbi.nlm.nih.gov/pubmed/32009153 http://dx.doi.org/10.1093/nar/gkaa004 |