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The relationship between preoperative predictive factors for clinical outcome in patients operated for lumbar spinal stenosis by decompressive laminectomy

BACKGROUND: Our hypothesis was that by identifying certain preoperative predictive factors, we could favorably impact clinical outcomes in patients undergoing decompressive surgery for lumbar spinal stenosis (LSS). METHODS: In this retrospective study, there were 65 patients (2016–2018) with symptom...

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Autores principales: Mauro, Dobran, Nasi, Davide, Paracino, Riccardo, Capece, Mara, Carrassi, Erika, Aiudi, Denis, Mancini, Fabrizio, Lattanzi, Simona, Colasanti, Roberto, Iacoangeli, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Scientific Scholar 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049892/
https://www.ncbi.nlm.nih.gov/pubmed/32123615
http://dx.doi.org/10.25259/SNI_583_2019
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author Mauro, Dobran
Nasi, Davide
Paracino, Riccardo
Capece, Mara
Carrassi, Erika
Aiudi, Denis
Mancini, Fabrizio
Lattanzi, Simona
Colasanti, Roberto
Iacoangeli, Maurizio
author_facet Mauro, Dobran
Nasi, Davide
Paracino, Riccardo
Capece, Mara
Carrassi, Erika
Aiudi, Denis
Mancini, Fabrizio
Lattanzi, Simona
Colasanti, Roberto
Iacoangeli, Maurizio
author_sort Mauro, Dobran
collection PubMed
description BACKGROUND: Our hypothesis was that by identifying certain preoperative predictive factors, we could favorably impact clinical outcomes in patients undergoing decompressive surgery for lumbar spinal stenosis (LSS). METHODS: In this retrospective study, there were 65 patients (2016–2018) with symptomatic LSS who underwent decompressive laminectomy without fusion. Their clinical outcomes were assessed utilizing the Oswestry Disability Index (ODI). Multiple preoperative variables were studied to determine which ones would help predict improved outcomes: gender, age, body mass index (BMI), general/neurological examination, smoking, and drug therapies (anxiolytics and/or antidepressants). RESULTS: All patients demonstrated statistically significant improvement on the ODI. Multivariate analysis revealed that those with higher preoperative BMI had significantly lower ODI on 1-year follow-up examinations, reflecting poorer outcomes. Postoperatively, 44 patients (67%) exhibited lower utilization of anxiolytic medications, 52 patients (80%) showed reduced use of antidepressant drugs, and pain medications utilization was reduced in 33 patients (50%). CONCLUSION: Decompressive laminectomy without fusion effectively managed LSS. It reduced patients’ use of pain, anxiety, and antidepressant medications. In addition, we found that increased preoperative BMIs contributed to poorer postoperative outcomes (e.g., ODI values).
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spelling pubmed-70498922020-03-02 The relationship between preoperative predictive factors for clinical outcome in patients operated for lumbar spinal stenosis by decompressive laminectomy Mauro, Dobran Nasi, Davide Paracino, Riccardo Capece, Mara Carrassi, Erika Aiudi, Denis Mancini, Fabrizio Lattanzi, Simona Colasanti, Roberto Iacoangeli, Maurizio Surg Neurol Int Original Article BACKGROUND: Our hypothesis was that by identifying certain preoperative predictive factors, we could favorably impact clinical outcomes in patients undergoing decompressive surgery for lumbar spinal stenosis (LSS). METHODS: In this retrospective study, there were 65 patients (2016–2018) with symptomatic LSS who underwent decompressive laminectomy without fusion. Their clinical outcomes were assessed utilizing the Oswestry Disability Index (ODI). Multiple preoperative variables were studied to determine which ones would help predict improved outcomes: gender, age, body mass index (BMI), general/neurological examination, smoking, and drug therapies (anxiolytics and/or antidepressants). RESULTS: All patients demonstrated statistically significant improvement on the ODI. Multivariate analysis revealed that those with higher preoperative BMI had significantly lower ODI on 1-year follow-up examinations, reflecting poorer outcomes. Postoperatively, 44 patients (67%) exhibited lower utilization of anxiolytic medications, 52 patients (80%) showed reduced use of antidepressant drugs, and pain medications utilization was reduced in 33 patients (50%). CONCLUSION: Decompressive laminectomy without fusion effectively managed LSS. It reduced patients’ use of pain, anxiety, and antidepressant medications. In addition, we found that increased preoperative BMIs contributed to poorer postoperative outcomes (e.g., ODI values). Scientific Scholar 2020-02-25 /pmc/articles/PMC7049892/ /pubmed/32123615 http://dx.doi.org/10.25259/SNI_583_2019 Text en Copyright: © 2020 Surgical Neurology International http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-Share Alike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Original Article
Mauro, Dobran
Nasi, Davide
Paracino, Riccardo
Capece, Mara
Carrassi, Erika
Aiudi, Denis
Mancini, Fabrizio
Lattanzi, Simona
Colasanti, Roberto
Iacoangeli, Maurizio
The relationship between preoperative predictive factors for clinical outcome in patients operated for lumbar spinal stenosis by decompressive laminectomy
title The relationship between preoperative predictive factors for clinical outcome in patients operated for lumbar spinal stenosis by decompressive laminectomy
title_full The relationship between preoperative predictive factors for clinical outcome in patients operated for lumbar spinal stenosis by decompressive laminectomy
title_fullStr The relationship between preoperative predictive factors for clinical outcome in patients operated for lumbar spinal stenosis by decompressive laminectomy
title_full_unstemmed The relationship between preoperative predictive factors for clinical outcome in patients operated for lumbar spinal stenosis by decompressive laminectomy
title_short The relationship between preoperative predictive factors for clinical outcome in patients operated for lumbar spinal stenosis by decompressive laminectomy
title_sort relationship between preoperative predictive factors for clinical outcome in patients operated for lumbar spinal stenosis by decompressive laminectomy
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049892/
https://www.ncbi.nlm.nih.gov/pubmed/32123615
http://dx.doi.org/10.25259/SNI_583_2019
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