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Activating transcription factor 4 (ATF4) promotes skeletal muscle atrophy by forming a heterodimer with the transcriptional regulator C/EBPβ
Skeletal muscle atrophy is a highly-prevalent and debilitating condition that remains poorly understood at the molecular level. Previous work found that aging, fasting, and immobilization promote skeletal muscle atrophy via expression of activating transcription factor 4 (ATF4) in skeletal muscle fi...
Autores principales: | Ebert, Scott M., Bullard, Steven A., Basisty, Nathan, Marcotte, George R., Skopec, Zachary P., Dierdorff, Jason M., Al-Zougbi, Asma, Tomcheck, Kristin C., DeLau, Austin D., Rathmacher, Jacob A., Bodine, Sue C., Schilling, Birgit, Adams, Christopher M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7049960/ https://www.ncbi.nlm.nih.gov/pubmed/31953319 http://dx.doi.org/10.1074/jbc.RA119.012095 |
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