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Breast cancer stromal clotting activation (Tissue Factor and thrombin): A pre‐invasive phenomena that is prognostic in invasion
BACKGROUND: Tumor stroma, of which fibroblasts are the most abundant cell, resembles a non‐healing wound, where a procoagulant environment creates a permissive milieu for cancer growth. We aimed to determine if tumor expression of coagulation factors (procoagulant phenotype), and systemic hypercoagu...
Autores principales: | Shaker, Hudhaifah, Bundred, Nigel J., Landberg, Göran, Pritchard, Susan A., Albadry, Harith, Nicholson, Sarah L., Harries, Lauren J., Heah, Jing Y. E., Castle, John, Kirwan, Cliona C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7050075/ https://www.ncbi.nlm.nih.gov/pubmed/31962001 http://dx.doi.org/10.1002/cam4.2748 |
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