Cargando…

Memory complaints and depressive symptoms over time: a construct-level replication analysis

BACKGROUND: Memory complaints and depressive symptoms are frequently associated in older adults and both serve as potential indicators of future cognitive decline. However, the temporal ordering of the development of these two symptoms remains unclear. The goal of the current study was to examine co...

Descripción completa

Detalles Bibliográficos
Autores principales: Mogle, Jacqueline, Hill, Nikki L., Bhargava, Sakshi, Bell, Tyler Reed, Bhang, Iris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7050122/
https://www.ncbi.nlm.nih.gov/pubmed/32114980
http://dx.doi.org/10.1186/s12877-020-1451-1
_version_ 1783502573779550208
author Mogle, Jacqueline
Hill, Nikki L.
Bhargava, Sakshi
Bell, Tyler Reed
Bhang, Iris
author_facet Mogle, Jacqueline
Hill, Nikki L.
Bhargava, Sakshi
Bell, Tyler Reed
Bhang, Iris
author_sort Mogle, Jacqueline
collection PubMed
description BACKGROUND: Memory complaints and depressive symptoms are frequently associated in older adults and both serve as potential indicators of future cognitive decline. However, the temporal ordering of the development of these two symptoms remains unclear. The goal of the current study was to examine concurrent and temporal relationships between memory complaints and depressive symptoms in older adults. METHODS: Data were drawn from two longitudinal, nationally representative datasets and included cognitively intact older adults aged 65 and over. The datasets in the current study were from the National Health and Aging Trends Study (NHATS) and the Health and Retirement Study (HRS). Using an integrative analytic framework, we tested bidirectional temporal relationships between memory complaints (memory ratings and perceived memory decline) and depressive symptoms over 6 to 9 years of data in over 5000 older adults across these two samples. RESULTS: Across both datasets, perceived memory decline predicted future depressive symptoms whereas memory ratings did not. Additionally, results showed that at times when depressive symptoms tended to be higher, memory complaints were also higher, but depressive symptoms did not predict future memory complaints. One finding that was inconsistent across datasets was memory ratings predicting depressive symptoms. After accounting for covariates, this relationship was only significant in one dataset. CONCLUSIONS: Cognitively intact older adults who report memory decline may be at risk for developing depressive symptoms in the future. Furthermore, our findings highlight the importance of using immediate replication of results across datasets to determine the generalizability of conclusions.
format Online
Article
Text
id pubmed-7050122
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-70501222020-03-05 Memory complaints and depressive symptoms over time: a construct-level replication analysis Mogle, Jacqueline Hill, Nikki L. Bhargava, Sakshi Bell, Tyler Reed Bhang, Iris BMC Geriatr Research Article BACKGROUND: Memory complaints and depressive symptoms are frequently associated in older adults and both serve as potential indicators of future cognitive decline. However, the temporal ordering of the development of these two symptoms remains unclear. The goal of the current study was to examine concurrent and temporal relationships between memory complaints and depressive symptoms in older adults. METHODS: Data were drawn from two longitudinal, nationally representative datasets and included cognitively intact older adults aged 65 and over. The datasets in the current study were from the National Health and Aging Trends Study (NHATS) and the Health and Retirement Study (HRS). Using an integrative analytic framework, we tested bidirectional temporal relationships between memory complaints (memory ratings and perceived memory decline) and depressive symptoms over 6 to 9 years of data in over 5000 older adults across these two samples. RESULTS: Across both datasets, perceived memory decline predicted future depressive symptoms whereas memory ratings did not. Additionally, results showed that at times when depressive symptoms tended to be higher, memory complaints were also higher, but depressive symptoms did not predict future memory complaints. One finding that was inconsistent across datasets was memory ratings predicting depressive symptoms. After accounting for covariates, this relationship was only significant in one dataset. CONCLUSIONS: Cognitively intact older adults who report memory decline may be at risk for developing depressive symptoms in the future. Furthermore, our findings highlight the importance of using immediate replication of results across datasets to determine the generalizability of conclusions. BioMed Central 2020-03-02 /pmc/articles/PMC7050122/ /pubmed/32114980 http://dx.doi.org/10.1186/s12877-020-1451-1 Text en © The Author(s). 2020 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Mogle, Jacqueline
Hill, Nikki L.
Bhargava, Sakshi
Bell, Tyler Reed
Bhang, Iris
Memory complaints and depressive symptoms over time: a construct-level replication analysis
title Memory complaints and depressive symptoms over time: a construct-level replication analysis
title_full Memory complaints and depressive symptoms over time: a construct-level replication analysis
title_fullStr Memory complaints and depressive symptoms over time: a construct-level replication analysis
title_full_unstemmed Memory complaints and depressive symptoms over time: a construct-level replication analysis
title_short Memory complaints and depressive symptoms over time: a construct-level replication analysis
title_sort memory complaints and depressive symptoms over time: a construct-level replication analysis
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7050122/
https://www.ncbi.nlm.nih.gov/pubmed/32114980
http://dx.doi.org/10.1186/s12877-020-1451-1
work_keys_str_mv AT moglejacqueline memorycomplaintsanddepressivesymptomsovertimeaconstructlevelreplicationanalysis
AT hillnikkil memorycomplaintsanddepressivesymptomsovertimeaconstructlevelreplicationanalysis
AT bhargavasakshi memorycomplaintsanddepressivesymptomsovertimeaconstructlevelreplicationanalysis
AT belltylerreed memorycomplaintsanddepressivesymptomsovertimeaconstructlevelreplicationanalysis
AT bhangiris memorycomplaintsanddepressivesymptomsovertimeaconstructlevelreplicationanalysis