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Cathepsin D Expression and Gemcitabine Resistance in Pancreatic Cancer

BACKGROUND: Cathepsin-D (CatD), owing to its dual role as a proteolytic enzyme and as a ligand, has been implicated in cancer progression. The role of CatD in pancreatic ductal adenocarcinoma is unknown. METHODS: CatD expression quantified by immunohistochemistry of tumor-tissue microarrays of 403 r...

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Detalles Bibliográficos
Autores principales:	Mahajan, Ujjwal M, Goni, Elisabetta, Langhoff, Enno, Li, Qi, Costello, Eithne, Greenhalf, William, Kruger, Stephan, Ormanns, Steffen, Halloran, Christopher, Ganeh, Paula, Marron, Manuela, Lämmerhirt, Felix, Zhao, Yue, Beyer, Georg, Weiss, Frank-Ulrich, Sendler, Matthias, Bruns, Christiane J, Kohlmann, Thomas, Kirchner, Thomas, Werner, Jens, D’Haese, Jan G, von Bergwelt-Baildon, Michael, Heinemann, Volker, Neoptolemos, John P, Büchler, Markus W, Belka, Claus, Boeck, Stefan, Lerch, Markus M, Mayerle, Julia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7050148/ https://www.ncbi.nlm.nih.gov/pubmed/32296755 http://dx.doi.org/10.1093/jncics/pkz060

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