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Crystal structure of botulinum neurotoxin subtype A3 cell binding domain in complex with GD1a co‐receptor ganglioside

Botulinum neurotoxins (BoNTs) are one of the most toxic proteins known to humans. Their molecular structure is comprised of three essential domains—a cell binding domain (H(C)), translocation domain and catalytic domain (light chain) . The H(C) domain facilitates the highly specific binding of BoNTs...

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Detalles Bibliográficos
Autores principales: Gregory, Kyle S., Liu, Sai Man, Acharya, K. Ravi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7050238/
https://www.ncbi.nlm.nih.gov/pubmed/31945264
http://dx.doi.org/10.1002/2211-5463.12790