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Crystal structure of botulinum neurotoxin subtype A3 cell binding domain in complex with GD1a co‐receptor ganglioside
Botulinum neurotoxins (BoNTs) are one of the most toxic proteins known to humans. Their molecular structure is comprised of three essential domains—a cell binding domain (H(C)), translocation domain and catalytic domain (light chain) . The H(C) domain facilitates the highly specific binding of BoNTs...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7050238/ https://www.ncbi.nlm.nih.gov/pubmed/31945264 http://dx.doi.org/10.1002/2211-5463.12790 |