Inhibition of MGAT2 modulates fat‐induced gut peptide release and fat intake in normal mice and ameliorates obesity and diabetes in ob/ob mice fed on a high‐fat diet

Monoacylglycerol O‐acyltransferase 2 (MGAT2) is one of the key enzymes responsible for triglyceride (TG) re‐synthesis in the small intestine. We have previously demonstrated that pharmacological inhibition of MGAT2 has beneficial effects on obesity and metabolic disorders in mice. Here, we further i...

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Detalles Bibliográficos
Autores principales: Mochida, Taisuke, Take, Kazumi, Maki, Toshiyuki, Nakakariya, Masanori, Adachi, Ryutaro, Sato, Kenjiro, Kitazaki, Tomoyuki, Takekawa, Shiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7050258/
https://www.ncbi.nlm.nih.gov/pubmed/31837122
http://dx.doi.org/10.1002/2211-5463.12778

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