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Risk of diabetic foot ulcer and its associated factors among Bangladeshi subjects: a multicentric cross-sectional study

OBJECTIVE: To assess the risk of diabetic foot ulcer (DFU) and find out its associated factors among subjects with type 2 diabetes (T2D) of Bangladesh. DESIGN, SETTING AND PARTICIPANTS: This cross-sectional study recruited 1200 subjects with T2D who visited 16 centres of Health Care Development Proj...

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Autores principales: Banik, Palash Chandra, Barua, Lingkan, Moniruzzaman, Mohammad, Mondal, Rajib, Zaman, Farhana, Ali, Liaquat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7050319/
https://www.ncbi.nlm.nih.gov/pubmed/32114471
http://dx.doi.org/10.1136/bmjopen-2019-034058
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author Banik, Palash Chandra
Barua, Lingkan
Moniruzzaman, Mohammad
Mondal, Rajib
Zaman, Farhana
Ali, Liaquat
author_facet Banik, Palash Chandra
Barua, Lingkan
Moniruzzaman, Mohammad
Mondal, Rajib
Zaman, Farhana
Ali, Liaquat
author_sort Banik, Palash Chandra
collection PubMed
description OBJECTIVE: To assess the risk of diabetic foot ulcer (DFU) and find out its associated factors among subjects with type 2 diabetes (T2D) of Bangladesh. DESIGN, SETTING AND PARTICIPANTS: This cross-sectional study recruited 1200 subjects with T2D who visited 16 centres of Health Care Development Project run by Diabetic Association of Bangladesh. PRIMARY AND SECONDARY OUTCOME MEASURES: Risk of DFU was assessed using a modified version of International Working Group on the Diabetic Foot (IWGDF) Risk Classification System. The modified system was based on five parameters, namely peripheral neuropathy (PN), peripheral arterial diseases (PAD), deformity, ulcer history and amputation. The risks were categorised as group 0 (no PN, no PAD), group 1 (PN, no PAD and no deformity), group 2A (PN and deformity, no PAD), group 2B (PAD), group 3A (ulcer history) and group 3B (amputation). The associated factors of DFU risk were determined using multinomial logistic regression for each risk category separately. RESULTS: Overall, 44.5% of the subjects were found ‘at risk’ of DFU. This risk was higher among men (45.6%) than women and among those who lived in rural areas (45.5%) as compared with the urban population. According to IWGDF categories, the risk was distributed as 55.5%, 4.2%, 11.6%, 0.3%, 20.6% and 7.9% for group 0, group 1, group 2A, group 2B, group 3A and group 3B, respectively. The associated factors of DFU (OR >1) were age ≥50 years, rural area, low economic status, insulin use, history of trauma, diabetic retinopathy and diabetic nephropathy. CONCLUSION: A significant number of the subjects with T2D under study were at risk of DFU, which demands an effective screening programme to reduce DFU-related morbidity and mortality.
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spelling pubmed-70503192020-03-16 Risk of diabetic foot ulcer and its associated factors among Bangladeshi subjects: a multicentric cross-sectional study Banik, Palash Chandra Barua, Lingkan Moniruzzaman, Mohammad Mondal, Rajib Zaman, Farhana Ali, Liaquat BMJ Open Diabetes and Endocrinology OBJECTIVE: To assess the risk of diabetic foot ulcer (DFU) and find out its associated factors among subjects with type 2 diabetes (T2D) of Bangladesh. DESIGN, SETTING AND PARTICIPANTS: This cross-sectional study recruited 1200 subjects with T2D who visited 16 centres of Health Care Development Project run by Diabetic Association of Bangladesh. PRIMARY AND SECONDARY OUTCOME MEASURES: Risk of DFU was assessed using a modified version of International Working Group on the Diabetic Foot (IWGDF) Risk Classification System. The modified system was based on five parameters, namely peripheral neuropathy (PN), peripheral arterial diseases (PAD), deformity, ulcer history and amputation. The risks were categorised as group 0 (no PN, no PAD), group 1 (PN, no PAD and no deformity), group 2A (PN and deformity, no PAD), group 2B (PAD), group 3A (ulcer history) and group 3B (amputation). The associated factors of DFU risk were determined using multinomial logistic regression for each risk category separately. RESULTS: Overall, 44.5% of the subjects were found ‘at risk’ of DFU. This risk was higher among men (45.6%) than women and among those who lived in rural areas (45.5%) as compared with the urban population. According to IWGDF categories, the risk was distributed as 55.5%, 4.2%, 11.6%, 0.3%, 20.6% and 7.9% for group 0, group 1, group 2A, group 2B, group 3A and group 3B, respectively. The associated factors of DFU (OR >1) were age ≥50 years, rural area, low economic status, insulin use, history of trauma, diabetic retinopathy and diabetic nephropathy. CONCLUSION: A significant number of the subjects with T2D under study were at risk of DFU, which demands an effective screening programme to reduce DFU-related morbidity and mortality. BMJ Publishing Group 2020-02-28 /pmc/articles/PMC7050319/ /pubmed/32114471 http://dx.doi.org/10.1136/bmjopen-2019-034058 Text en © Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.
spellingShingle Diabetes and Endocrinology
Banik, Palash Chandra
Barua, Lingkan
Moniruzzaman, Mohammad
Mondal, Rajib
Zaman, Farhana
Ali, Liaquat
Risk of diabetic foot ulcer and its associated factors among Bangladeshi subjects: a multicentric cross-sectional study
title Risk of diabetic foot ulcer and its associated factors among Bangladeshi subjects: a multicentric cross-sectional study
title_full Risk of diabetic foot ulcer and its associated factors among Bangladeshi subjects: a multicentric cross-sectional study
title_fullStr Risk of diabetic foot ulcer and its associated factors among Bangladeshi subjects: a multicentric cross-sectional study
title_full_unstemmed Risk of diabetic foot ulcer and its associated factors among Bangladeshi subjects: a multicentric cross-sectional study
title_short Risk of diabetic foot ulcer and its associated factors among Bangladeshi subjects: a multicentric cross-sectional study
title_sort risk of diabetic foot ulcer and its associated factors among bangladeshi subjects: a multicentric cross-sectional study
topic Diabetes and Endocrinology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7050319/
https://www.ncbi.nlm.nih.gov/pubmed/32114471
http://dx.doi.org/10.1136/bmjopen-2019-034058
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