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Management of vernal keratoconjunctivitis in children in Saudi Arabia

Vernal keratoconjunctivitis is a chronic inflammatory disease of the ocular surface and one of the worst types of allergic conjunctival diseases. Because of its chronic nature, it can damage the cornea, resulting in sight-threatening complications if left untreated. The disease affects mainly young...

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Autor principal: AlHarkan, Dora Hamad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7050462/
https://www.ncbi.nlm.nih.gov/pubmed/32174733
http://dx.doi.org/10.4103/ojo.OJO_263_2018
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author AlHarkan, Dora Hamad
author_facet AlHarkan, Dora Hamad
author_sort AlHarkan, Dora Hamad
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description Vernal keratoconjunctivitis is a chronic inflammatory disease of the ocular surface and one of the worst types of allergic conjunctival diseases. Because of its chronic nature, it can damage the cornea, resulting in sight-threatening complications if left untreated. The disease affects mainly young children starting around the age of 7 years. We used keywords to search for published English articles in PUBMED, Google Scholar, EMBASE, and Cochrane Database of Systematic Reviews. Most of the published literature is focusing on general management of the disease and few publications focusing on treatment in the pediatric age group. We highlight the importance of how is the topical management differs between age groups. We focused on the importance of doing cycloplegic refraction for each child as the risk of keratoconus and oblique astigmatism is high in these cases. Furthermore, we highlight the importance of using eye lubricants as a therapeutic and preventive tool for the attacks of the disease. We highlight that most of the recent effective medications (especially the off-label ones) are not available in Saudi Arabia, such as tacrolimus, and some are only available to be prepared in tertiary center pharmacies as Cyclosporine A with higher concentrations.
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spelling pubmed-70504622020-03-13 Management of vernal keratoconjunctivitis in children in Saudi Arabia AlHarkan, Dora Hamad Oman J Ophthalmol Review Article Vernal keratoconjunctivitis is a chronic inflammatory disease of the ocular surface and one of the worst types of allergic conjunctival diseases. Because of its chronic nature, it can damage the cornea, resulting in sight-threatening complications if left untreated. The disease affects mainly young children starting around the age of 7 years. We used keywords to search for published English articles in PUBMED, Google Scholar, EMBASE, and Cochrane Database of Systematic Reviews. Most of the published literature is focusing on general management of the disease and few publications focusing on treatment in the pediatric age group. We highlight the importance of how is the topical management differs between age groups. We focused on the importance of doing cycloplegic refraction for each child as the risk of keratoconus and oblique astigmatism is high in these cases. Furthermore, we highlight the importance of using eye lubricants as a therapeutic and preventive tool for the attacks of the disease. We highlight that most of the recent effective medications (especially the off-label ones) are not available in Saudi Arabia, such as tacrolimus, and some are only available to be prepared in tertiary center pharmacies as Cyclosporine A with higher concentrations. Wolters Kluwer - Medknow 2020-02-17 /pmc/articles/PMC7050462/ /pubmed/32174733 http://dx.doi.org/10.4103/ojo.OJO_263_2018 Text en Copyright: © 2020 Oman Ophthalmic Society http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Review Article
AlHarkan, Dora Hamad
Management of vernal keratoconjunctivitis in children in Saudi Arabia
title Management of vernal keratoconjunctivitis in children in Saudi Arabia
title_full Management of vernal keratoconjunctivitis in children in Saudi Arabia
title_fullStr Management of vernal keratoconjunctivitis in children in Saudi Arabia
title_full_unstemmed Management of vernal keratoconjunctivitis in children in Saudi Arabia
title_short Management of vernal keratoconjunctivitis in children in Saudi Arabia
title_sort management of vernal keratoconjunctivitis in children in saudi arabia
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7050462/
https://www.ncbi.nlm.nih.gov/pubmed/32174733
http://dx.doi.org/10.4103/ojo.OJO_263_2018
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