Ancestry-agnostic estimation of DNA sample contamination from sequence reads

Detecting and estimating DNA sample contamination are important steps to ensure high-quality genotype calls and reliable downstream analysis. Existing methods rely on population allele frequency information for accurate estimation of contamination rates. Correctly specifying population allele freque...

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Detalles Bibliográficos
Autores principales: Zhang, Fan, Flickinger, Matthew, Taliun, Sarah A. Gagliano, Abecasis, Gonçalo R., Scott, Laura J., McCaroll, Steven A., Pato, Carlos N., Boehnke, Michael, Kang, Hyun Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7050530/
https://www.ncbi.nlm.nih.gov/pubmed/31980570
http://dx.doi.org/10.1101/gr.246934.118

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