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A review on bacterial resistance to carbapenems: epidemiology, detection and treatment options

Carbapenems are a class of antimicrobial agents reserved for infections caused by multidrug-resistant microorganisms. The emergence of carbapenem resistance has become a serious public health threat. This type of antimicrobial resistance is spreading at an alarming rate, resulting in major outbreaks...

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Detalles Bibliográficos
Autores principales: Elshamy, Ann A, Aboshanab, Khaled M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Science Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7050608/
https://www.ncbi.nlm.nih.gov/pubmed/32140243
http://dx.doi.org/10.2144/fsoa-2019-0098
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author Elshamy, Ann A
Aboshanab, Khaled M
author_facet Elshamy, Ann A
Aboshanab, Khaled M
author_sort Elshamy, Ann A
collection PubMed
description Carbapenems are a class of antimicrobial agents reserved for infections caused by multidrug-resistant microorganisms. The emergence of carbapenem resistance has become a serious public health threat. This type of antimicrobial resistance is spreading at an alarming rate, resulting in major outbreaks and treatment failure of community-acquired and nosocomial infections caused by the clinically relevant carbapenem-producing Enterobacteriaceae or carbapenem-resistant Enterobacteriaceae. This review is focused on carbapenem resistance, including mechanisms of resistance, history and epidemiology, phenotypic and genotypic detection in the clinically relevant bacterial pathogens and the possible treatment options available.
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spelling pubmed-70506082020-03-05 A review on bacterial resistance to carbapenems: epidemiology, detection and treatment options Elshamy, Ann A Aboshanab, Khaled M Future Sci OA Review Carbapenems are a class of antimicrobial agents reserved for infections caused by multidrug-resistant microorganisms. The emergence of carbapenem resistance has become a serious public health threat. This type of antimicrobial resistance is spreading at an alarming rate, resulting in major outbreaks and treatment failure of community-acquired and nosocomial infections caused by the clinically relevant carbapenem-producing Enterobacteriaceae or carbapenem-resistant Enterobacteriaceae. This review is focused on carbapenem resistance, including mechanisms of resistance, history and epidemiology, phenotypic and genotypic detection in the clinically relevant bacterial pathogens and the possible treatment options available. Future Science Ltd 2020-01-27 /pmc/articles/PMC7050608/ /pubmed/32140243 http://dx.doi.org/10.2144/fsoa-2019-0098 Text en © 2020 Ann A Elshamy & Khaled M Aboshanab This work is licensed under the Creative Commons Attribution 4.0 License (http://creativecommons.org/licenses/by/4.0/)
spellingShingle Review
Elshamy, Ann A
Aboshanab, Khaled M
A review on bacterial resistance to carbapenems: epidemiology, detection and treatment options
title A review on bacterial resistance to carbapenems: epidemiology, detection and treatment options
title_full A review on bacterial resistance to carbapenems: epidemiology, detection and treatment options
title_fullStr A review on bacterial resistance to carbapenems: epidemiology, detection and treatment options
title_full_unstemmed A review on bacterial resistance to carbapenems: epidemiology, detection and treatment options
title_short A review on bacterial resistance to carbapenems: epidemiology, detection and treatment options
title_sort review on bacterial resistance to carbapenems: epidemiology, detection and treatment options
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7050608/
https://www.ncbi.nlm.nih.gov/pubmed/32140243
http://dx.doi.org/10.2144/fsoa-2019-0098
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