Cargando…
Angiotensin II promotes podocyte injury by activating Arf6-Erk1/2-Nox4 signaling pathway
Angiotensin II (Ang II) is a key contributor to glomerular disease by predominantly resulting in podocyte injury, whereas the underlying molecular mechanisms has not been fully understood. This study aimed to investigate if and how ADP-ribosylation factor 6 (Arf6), a small GTP-binding protein, invol...
Autores principales: | Che, Guanghua, Gao, Hang, Hu, Qibo, Xie, Hongchang, Zhang, Yunfeng |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7051060/ https://www.ncbi.nlm.nih.gov/pubmed/32119711 http://dx.doi.org/10.1371/journal.pone.0229747 |
Ejemplares similares
-
High glucose induces Nox4 expression and podocyte apoptosis through the Smad3/ezrin/PKA pathway
por: Guo, Wanxu, et al.
Publicado: (2021) -
Angiotensin II induces cholesterol accumulation and injury in podocytes
por: Yang, Yingjie, et al.
Publicado: (2017) -
Sirt6 deficiency aggravates angiotensin II-induced cholesterol accumulation and injury in podocytes
por: Yang, Qian, et al.
Publicado: (2020) -
Angiotensin II Modulates Podocyte Glucose Transport
por: Lewko, Barbara, et al.
Publicado: (2018) -
ARF6 mediates nephrin tyrosine phosphorylation-induced podocyte cellular dynamics
por: Lin, Jamie S., et al.
Publicado: (2017)