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In silico analysis of the tryptophan hydroxylase 2 (TPH2) protein variants related to psychiatric disorders

The tryptophan hydroxylase 2 (TPH2) enzyme catalyzes the first step of serotonin biosynthesis. Serotonin is known for its role in several homeostatic systems related to sleep, mood, and food intake. As the reaction catalyzed by TPH2 is the rate-limiting step of serotonin biosynthesis, mutations in T...

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Detalles Bibliográficos
Autores principales:	Pereira, Gabriel Rodrigues Coutinho, Tavares, Gustavo Duarte Bocayuva, de Freitas, Marta Costa, De Mesquita, Joelma Freire
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7051086/ https://www.ncbi.nlm.nih.gov/pubmed/32119710 http://dx.doi.org/10.1371/journal.pone.0229730

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