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Inflammatory Bowel Disease and Obstructive Pulmonary Disease: A Two-way Association?

Inflammatory bowel diseases (IBD) is an umbrella term that covers both ulcerative colitis (UC) and Crohn's disease (CD), which are chronic inflammatory conditions of the gastrointestinal system. Airway diseases are one of the most commonly studied manifestations of IBD. It is observed that popu...

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Autores principales: Zergham, Azka Shahid, Sekhon, Amanpreet Kaur, Mebasher, Amal, Tserenpil, Gantuya, Malik, Bilal Haider
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7051109/
https://www.ncbi.nlm.nih.gov/pubmed/32181078
http://dx.doi.org/10.7759/cureus.6836
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author Zergham, Azka Shahid
Sekhon, Amanpreet Kaur
Mebasher, Amal
Tserenpil, Gantuya
Malik, Bilal Haider
author_facet Zergham, Azka Shahid
Sekhon, Amanpreet Kaur
Mebasher, Amal
Tserenpil, Gantuya
Malik, Bilal Haider
author_sort Zergham, Azka Shahid
collection PubMed
description Inflammatory bowel diseases (IBD) is an umbrella term that covers both ulcerative colitis (UC) and Crohn's disease (CD), which are chronic inflammatory conditions of the gastrointestinal system. Airway diseases are one of the most commonly studied manifestations of IBD. It is observed that populations with pre-existing obstructive pulmonary conditions are at higher risk of new-onset IBD. This newly documented evidence of increased incidence of IBD among patients with pulmonary diseases and the higher than the estimated prevalence of pulmonary diseases among IBD sufferers support the hypothesis of a two-way association. This review article focuses on summarizing the current knowledge and available evidence regarding the association between IBD and obstructive pulmonary diseases such as chronic obstructive pulmonary disease (COPD), emphysema, bronchiectasis, and asthma. We utilized PubMed as the primary search source and database and included the free full-text articles available on it, published over the past five years. We reviewed literature from multiple regions of the world, such as the US, UK, China, and Canada and compiled this traditional review article utilizing the information collected from 4,966,459 patients. Specifications such as age and gender were not mentioned in all articles. This review will serve to strengthen the existing research database concerning the relationship between IBD and obstructive pulmonary diseases. It will help to highlight the significance of the two-way association between IBD and obstructive pulmonary disease and the importance of treating these two conditions simultaneously. It will also raise awareness about the importance of timely detection of IBD and associated airway complications, leading to decreased disease burden and the treatment cost.
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spelling pubmed-70511092020-03-16 Inflammatory Bowel Disease and Obstructive Pulmonary Disease: A Two-way Association? Zergham, Azka Shahid Sekhon, Amanpreet Kaur Mebasher, Amal Tserenpil, Gantuya Malik, Bilal Haider Cureus Pathology Inflammatory bowel diseases (IBD) is an umbrella term that covers both ulcerative colitis (UC) and Crohn's disease (CD), which are chronic inflammatory conditions of the gastrointestinal system. Airway diseases are one of the most commonly studied manifestations of IBD. It is observed that populations with pre-existing obstructive pulmonary conditions are at higher risk of new-onset IBD. This newly documented evidence of increased incidence of IBD among patients with pulmonary diseases and the higher than the estimated prevalence of pulmonary diseases among IBD sufferers support the hypothesis of a two-way association. This review article focuses on summarizing the current knowledge and available evidence regarding the association between IBD and obstructive pulmonary diseases such as chronic obstructive pulmonary disease (COPD), emphysema, bronchiectasis, and asthma. We utilized PubMed as the primary search source and database and included the free full-text articles available on it, published over the past five years. We reviewed literature from multiple regions of the world, such as the US, UK, China, and Canada and compiled this traditional review article utilizing the information collected from 4,966,459 patients. Specifications such as age and gender were not mentioned in all articles. This review will serve to strengthen the existing research database concerning the relationship between IBD and obstructive pulmonary diseases. It will help to highlight the significance of the two-way association between IBD and obstructive pulmonary disease and the importance of treating these two conditions simultaneously. It will also raise awareness about the importance of timely detection of IBD and associated airway complications, leading to decreased disease burden and the treatment cost. Cureus 2020-01-31 /pmc/articles/PMC7051109/ /pubmed/32181078 http://dx.doi.org/10.7759/cureus.6836 Text en Copyright © 2020, Zergham et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Pathology
Zergham, Azka Shahid
Sekhon, Amanpreet Kaur
Mebasher, Amal
Tserenpil, Gantuya
Malik, Bilal Haider
Inflammatory Bowel Disease and Obstructive Pulmonary Disease: A Two-way Association?
title Inflammatory Bowel Disease and Obstructive Pulmonary Disease: A Two-way Association?
title_full Inflammatory Bowel Disease and Obstructive Pulmonary Disease: A Two-way Association?
title_fullStr Inflammatory Bowel Disease and Obstructive Pulmonary Disease: A Two-way Association?
title_full_unstemmed Inflammatory Bowel Disease and Obstructive Pulmonary Disease: A Two-way Association?
title_short Inflammatory Bowel Disease and Obstructive Pulmonary Disease: A Two-way Association?
title_sort inflammatory bowel disease and obstructive pulmonary disease: a two-way association?
topic Pathology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7051109/
https://www.ncbi.nlm.nih.gov/pubmed/32181078
http://dx.doi.org/10.7759/cureus.6836
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