Cargando…
Why does a mitochondrion need its individual cristae to be functionally autonomous?
We demonstrated that individual cristae in one mitochondrion function as autonomous electrochemical units, with this autonomy being maintained by cristae junction modulators. Here, I will summarize our novel findings, discuss the advantages of cristae insulation and reconcile this newly characterize...
| Autor principal: | |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7051166/ https://www.ncbi.nlm.nih.gov/pubmed/32158918 http://dx.doi.org/10.1080/23723556.2019.1705119 |
| _version_ | 1783502723140812800 |
|---|---|
| author | Liesa, Marc |
| author_facet | Liesa, Marc |
| author_sort | Liesa, Marc |
| collection | PubMed |
| description | We demonstrated that individual cristae in one mitochondrion function as autonomous electrochemical units, with this autonomy being maintained by cristae junction modulators. Here, I will summarize our novel findings, discuss the advantages of cristae insulation and reconcile this newly characterized cristae autonomy with previous studies showing coordinated cristae function. |
| format | Online Article Text |
| id | pubmed-7051166 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2020 |
| publisher | Taylor & Francis |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-70511662020-09-28 Why does a mitochondrion need its individual cristae to be functionally autonomous? Liesa, Marc Mol Cell Oncol Author's Views We demonstrated that individual cristae in one mitochondrion function as autonomous electrochemical units, with this autonomy being maintained by cristae junction modulators. Here, I will summarize our novel findings, discuss the advantages of cristae insulation and reconcile this newly characterized cristae autonomy with previous studies showing coordinated cristae function. Taylor & Francis 2020-01-10 /pmc/articles/PMC7051166/ /pubmed/32158918 http://dx.doi.org/10.1080/23723556.2019.1705119 Text en © 2020 The Author(s). Published with license by Taylor & Francis Group, LLC. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| spellingShingle | Author's Views Liesa, Marc Why does a mitochondrion need its individual cristae to be functionally autonomous? |
| title | Why does a mitochondrion need its individual cristae to be functionally autonomous? |
| title_full | Why does a mitochondrion need its individual cristae to be functionally autonomous? |
| title_fullStr | Why does a mitochondrion need its individual cristae to be functionally autonomous? |
| title_full_unstemmed | Why does a mitochondrion need its individual cristae to be functionally autonomous? |
| title_short | Why does a mitochondrion need its individual cristae to be functionally autonomous? |
| title_sort | why does a mitochondrion need its individual cristae to be functionally autonomous? |
| topic | Author's Views |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7051166/ https://www.ncbi.nlm.nih.gov/pubmed/32158918 http://dx.doi.org/10.1080/23723556.2019.1705119 |
| work_keys_str_mv | AT liesamarc whydoesamitochondrionneeditsindividualcristaetobefunctionallyautonomous |