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Valproic acid attenuates CCR2-dependent tumor infiltration of monocytic myeloid-derived suppressor cells, limiting tumor progression

Myeloid-derived suppressor cells (MDSCs) are immunosuppressive cells that promote tumor progression by inhibiting anti-tumor immunity and may be the cause of patient resistance to immune checkpoint inhibitors (ICIs). Therefore, MDSCs are a promising target for cancer immunotherapy, especially in com...

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Detalles Bibliográficos
Autores principales: Xie, Zhiqi, Ikegami, Tamami, Ago, Yukio, Okada, Naoki, Tachibana, Masashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7051186/
https://www.ncbi.nlm.nih.gov/pubmed/32158627
http://dx.doi.org/10.1080/2162402X.2020.1734268

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