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Xenogeneic Neu5Gc and self-glycan Neu5Ac epitopes are potential immune targets in MS
OBJECTIVE: To explore the repertoire of glycan-specific immunoglobulin G (IgG) antibodies in treatment-naive patients with relapsing-remitting multiple sclerosis (RRMS). METHODS: A systems-level approach combined with glycan array technologies was used to determine specificities and binding reactivi...
Autores principales: | Boligan, Kayluz F., Oechtering, Johanna, Keller, Christian W., Peschke, Benjamin, Rieben, Robert, Bovin, Nicolai, Kappos, Ludwig, Cummings, Richard D., Kuhle, Jens, von Gunten, Stephan, Lünemann, Jan D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7051216/ https://www.ncbi.nlm.nih.gov/pubmed/32014849 http://dx.doi.org/10.1212/NXI.0000000000000676 |
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