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Prophylactic, preemptive, and curative treatment for sinusoidal obstruction syndrome/veno-occlusive disease in adult patients: a position statement from an international expert group
Sinusoidal obstruction syndrome, also known as veno-occlusive disease (SOS/VOD), is a potentially life-threatening complication that can develop after hematopoietic cell transplantation (HCT). While SOS/VOD may resolve within a few weeks in the majority of patients with mild-to-moderate disease, the...
| Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7051913/ https://www.ncbi.nlm.nih.gov/pubmed/31576023 http://dx.doi.org/10.1038/s41409-019-0705-z |
| _version_ | 1783502757057003520 |
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| author | Mohty, Mohamad Malard, Florent Abecasis, Manuel Aerts, Erik Alaskar, Ahmed S. Aljurf, Mahmoud Arat, Mutlu Bader, Peter Baron, Frederic Basak, Grzegorz Bazarbachi, Ali Blaise, Didier Ciceri, Fabio Corbacioglu, Selim Dalle, Jean-Hugues Dignan, Fiona Fukuda, Takahiro Huynh, Anne Kuball, Jurgen Lachance, Silvy Lazarus, Hillard Masszi, Tamas Michallet, Mauricette Nagler, Arnon NiChonghaile, Mairead Okamoto, Shinichiro Pagliuca, Antonio Peters, Christina Petersen, Finn B. Richardson, Paul G. Ruutu, Tapani Saber, Wael Savani, Bipin N. Soiffer, Robert Styczynski, Jan Wallhult, Elisabeth Yakoub-Agha, Ibrahim Duarte, Rafael F. Carreras, Enric |
| author_facet | Mohty, Mohamad Malard, Florent Abecasis, Manuel Aerts, Erik Alaskar, Ahmed S. Aljurf, Mahmoud Arat, Mutlu Bader, Peter Baron, Frederic Basak, Grzegorz Bazarbachi, Ali Blaise, Didier Ciceri, Fabio Corbacioglu, Selim Dalle, Jean-Hugues Dignan, Fiona Fukuda, Takahiro Huynh, Anne Kuball, Jurgen Lachance, Silvy Lazarus, Hillard Masszi, Tamas Michallet, Mauricette Nagler, Arnon NiChonghaile, Mairead Okamoto, Shinichiro Pagliuca, Antonio Peters, Christina Petersen, Finn B. Richardson, Paul G. Ruutu, Tapani Saber, Wael Savani, Bipin N. Soiffer, Robert Styczynski, Jan Wallhult, Elisabeth Yakoub-Agha, Ibrahim Duarte, Rafael F. Carreras, Enric |
| author_sort | Mohty, Mohamad |
| collection | PubMed |
| description | Sinusoidal obstruction syndrome, also known as veno-occlusive disease (SOS/VOD), is a potentially life-threatening complication that can develop after hematopoietic cell transplantation (HCT). While SOS/VOD may resolve within a few weeks in the majority of patients with mild-to-moderate disease, the most severe forms result in multiorgan dysfunction and are associated with a high mortality rate (>80%). Therefore, careful surveillance may allow early detection of SOS/VOD, particularly as the licensed available drug is proven to be effective and reduce mortality. The aim of this work is to propose an international consensus guideline for the treatment and prevention of SOS/VOD in adult patients, on behalf of an international expert group. |
| format | Online Article Text |
| id | pubmed-7051913 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2019 |
| publisher | Nature Publishing Group UK |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-70519132020-03-05 Prophylactic, preemptive, and curative treatment for sinusoidal obstruction syndrome/veno-occlusive disease in adult patients: a position statement from an international expert group Mohty, Mohamad Malard, Florent Abecasis, Manuel Aerts, Erik Alaskar, Ahmed S. Aljurf, Mahmoud Arat, Mutlu Bader, Peter Baron, Frederic Basak, Grzegorz Bazarbachi, Ali Blaise, Didier Ciceri, Fabio Corbacioglu, Selim Dalle, Jean-Hugues Dignan, Fiona Fukuda, Takahiro Huynh, Anne Kuball, Jurgen Lachance, Silvy Lazarus, Hillard Masszi, Tamas Michallet, Mauricette Nagler, Arnon NiChonghaile, Mairead Okamoto, Shinichiro Pagliuca, Antonio Peters, Christina Petersen, Finn B. Richardson, Paul G. Ruutu, Tapani Saber, Wael Savani, Bipin N. Soiffer, Robert Styczynski, Jan Wallhult, Elisabeth Yakoub-Agha, Ibrahim Duarte, Rafael F. Carreras, Enric Bone Marrow Transplant Feature Sinusoidal obstruction syndrome, also known as veno-occlusive disease (SOS/VOD), is a potentially life-threatening complication that can develop after hematopoietic cell transplantation (HCT). While SOS/VOD may resolve within a few weeks in the majority of patients with mild-to-moderate disease, the most severe forms result in multiorgan dysfunction and are associated with a high mortality rate (>80%). Therefore, careful surveillance may allow early detection of SOS/VOD, particularly as the licensed available drug is proven to be effective and reduce mortality. The aim of this work is to propose an international consensus guideline for the treatment and prevention of SOS/VOD in adult patients, on behalf of an international expert group. Nature Publishing Group UK 2019-10-01 2020 /pmc/articles/PMC7051913/ /pubmed/31576023 http://dx.doi.org/10.1038/s41409-019-0705-z Text en © The Author(s) 2019 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
| spellingShingle | Feature Mohty, Mohamad Malard, Florent Abecasis, Manuel Aerts, Erik Alaskar, Ahmed S. Aljurf, Mahmoud Arat, Mutlu Bader, Peter Baron, Frederic Basak, Grzegorz Bazarbachi, Ali Blaise, Didier Ciceri, Fabio Corbacioglu, Selim Dalle, Jean-Hugues Dignan, Fiona Fukuda, Takahiro Huynh, Anne Kuball, Jurgen Lachance, Silvy Lazarus, Hillard Masszi, Tamas Michallet, Mauricette Nagler, Arnon NiChonghaile, Mairead Okamoto, Shinichiro Pagliuca, Antonio Peters, Christina Petersen, Finn B. Richardson, Paul G. Ruutu, Tapani Saber, Wael Savani, Bipin N. Soiffer, Robert Styczynski, Jan Wallhult, Elisabeth Yakoub-Agha, Ibrahim Duarte, Rafael F. Carreras, Enric Prophylactic, preemptive, and curative treatment for sinusoidal obstruction syndrome/veno-occlusive disease in adult patients: a position statement from an international expert group |
| title | Prophylactic, preemptive, and curative treatment for sinusoidal obstruction syndrome/veno-occlusive disease in adult patients: a position statement from an international expert group |
| title_full | Prophylactic, preemptive, and curative treatment for sinusoidal obstruction syndrome/veno-occlusive disease in adult patients: a position statement from an international expert group |
| title_fullStr | Prophylactic, preemptive, and curative treatment for sinusoidal obstruction syndrome/veno-occlusive disease in adult patients: a position statement from an international expert group |
| title_full_unstemmed | Prophylactic, preemptive, and curative treatment for sinusoidal obstruction syndrome/veno-occlusive disease in adult patients: a position statement from an international expert group |
| title_short | Prophylactic, preemptive, and curative treatment for sinusoidal obstruction syndrome/veno-occlusive disease in adult patients: a position statement from an international expert group |
| title_sort | prophylactic, preemptive, and curative treatment for sinusoidal obstruction syndrome/veno-occlusive disease in adult patients: a position statement from an international expert group |
| topic | Feature |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7051913/ https://www.ncbi.nlm.nih.gov/pubmed/31576023 http://dx.doi.org/10.1038/s41409-019-0705-z |
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