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Conducting a Virtual Clinical Trial in HER2-Negative Breast Cancer Using a Quantitative Systems Pharmacology Model With an Epigenetic Modulator and Immune Checkpoint Inhibitors

The survival rate of patients with breast cancer has been improved by immune checkpoint blockade therapies, and the efficacy of their combinations with epigenetic modulators has shown promising results in preclinical studies. In this prospective study, we propose an ordinary differential equation (O...

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Detalles Bibliográficos
Autores principales:	Wang, Hanwen, Sové, Richard J., Jafarnejad, Mohammad, Rahmeh, Sondra, Jaffee, Elizabeth M., Stearns, Vered, Torres, Evanthia T. Roussos, Connolly, Roisin M., Popel, Aleksander S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Bioengineering and Biotechnology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7051945/ https://www.ncbi.nlm.nih.gov/pubmed/32158754 http://dx.doi.org/10.3389/fbioe.2020.00141

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