Enhanced DNA-repair capacity and resistance to chemically induced carcinogenesis upon deletion of the phosphatase regulator NIPP1

Nuclear Inhibitor of PP1 (NIPP1) is a conserved regulatory subunit of protein phosphatase PP1. The selective deletion of NIPP1 in mouse liver parenchymal cells or skin epidermal cells culminates in a late-onset hyperproliferation of a subset of resident progenitor cells. Although a hyperplastic phen...

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Detalles Bibliográficos
Autores principales: Verbinnen, Iris, Boens, Shannah, Ferreira, Monica, Szekér, Kathelijne, Van Wijk, Louise, Van Eynde, Aleyde, Bollen, Mathieu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7051951/
https://www.ncbi.nlm.nih.gov/pubmed/32123159
http://dx.doi.org/10.1038/s41389-020-0214-3

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