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High-resolution imaging mass spectrometry combined with transcriptomic analysis identified a link between fatty acid composition of phosphatidylinositols and the immune checkpoint pathway at the primary tumour site of breast cancer

BACKGROUND: The fatty acid (FA) composition of phosphatidylinositols (PIs) is tightly regulated in mammalian tissue since its disruption impairs normal cellular functions. We previously found its significant alteration in breast cancer by using matrix-assisted laser desorption and ionisation imaging...

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Detalles Bibliográficos
Autores principales:	Kawashima, Masahiro, Tokiwa, Mariko, Nishimura, Tomomi, Kawata, Yukiko, Sugimoto, Masahiro, Kataoka, Tatsuki R., Sakurai, Takaki, Iwaisako, Keiko, Suzuki, Eiji, Hagiwara, Masatoshi, Harris, Adrian L., Toi, Masakazu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7051979/ https://www.ncbi.nlm.nih.gov/pubmed/31819188 http://dx.doi.org/10.1038/s41416-019-0662-8

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