Cargando…

Bungeanum Improves Cognitive Dysfunction and Neurological Deficits in D-Galactose-Induced Aging Mice via Activating PI3K/Akt/Nrf2 Signaling Pathway

Zanthoxylum bungeanum Maxim (Rutaceae), a popular condiment and dietetic herbal medicine, has been used traditionally in the treatment of forgetfulness, as recorded in Shen Nong's Herbal Medicine, an old Chinese medicine book. To explore effects and potential mechanisms of it, extracts of Z. bu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhao, Meihuan, Tang, Xueqian, Gong, Daoying, Xia, Peng, Wang, Fushun, Xu, Shijun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052015/ https://www.ncbi.nlm.nih.gov/pubmed/32158388 http://dx.doi.org/10.3389/fphar.2020.00071

Ejemplares similares

Protective effects and mechanism of puerarin targeting PI3K/Akt signal pathway on neurological diseases
por: Wang, Qian, et al.
Publicado: (2022)

Hydroxy-α-sanshool isolated from Zanthoxylum bungeanum Maxim. has antidiabetic effects on high-fat-fed and streptozotocin-treated mice via increasing glycogen synthesis by regulation of PI3K/Akt/GSK-3β/GS signaling
por: Zhang, Qing, et al.
Publicado: (2022)

Formononetin Improves the Survival of Random Skin Flaps Through PI3K/Akt-Mediated Nrf2 Antioxidant Defense System
por: Li, Haoliang, et al.
Publicado: (2022)

Echinocystic acid alleviated hypoxic-ischemic brain damage in neonatal mice by activating the PI3K/Akt/Nrf2 signaling pathway
por: Li, Yuan, et al.
Publicado: (2023)

Puerarin inhibited oxidative stress and alleviated cerebral ischemia-reperfusion injury through PI3K/Akt/Nrf2 signaling pathway
por: Zhang, Qianqian, et al.
Publicado: (2023)

Network Pharmacology-Based Strategy for the Investigation of the Anti-Obesity Effects of an Ethanolic Extract of Zanthoxylum bungeanum Maxim
por: Wang, Ying, et al.
Publicado: (2020)

Nrf2 Signaling Pathway Mediates the Protective Effects of Daphnetin Against D-Galactose Induced-Premature Ovarian Failure
por: Zhang, Mengwen, et al.
Publicado: (2022)

Metformin Promotes Differentiation and Attenuates H(2)O(2)-Induced Oxidative Damage of Osteoblasts via the PI3K/AKT/Nrf2/HO-1 Pathway
por: Yang, Keda, et al.
Publicado: (2022)

Comparing PI3K/Akt Inhibitors Used in Ovarian Cancer Treatment
por: Wu, Yi-Hui, et al.
Publicado: (2020)

Celastrol Alleviates Autoimmune Hepatitis Through the PI3K/AKT Signaling Pathway Based on Network Pharmacology and Experiments
por: Wang, Shuhui, et al.
Publicado: (2022)

Baicalin Attenuates Oxygen–Glucose Deprivation/Reoxygenation–Induced Injury by Modulating the BDNF-TrkB/PI3K/Akt and MAPK/Erk1/2 Signaling Axes in Neuron–Astrocyte Cocultures
por: Li, Changxiang, et al.
Publicado: (2021)

Terpenoid natural products exert neuroprotection via the PI3K/Akt pathway
por: Xu, Bingyao, et al.
Publicado: (2022)

Progression of the PI3K/Akt signaling pathway in chronic obstructive pulmonary disease
por: Liu, Yanhui, et al.
Publicado: (2023)

rhKGF-2 Attenuates Smoke Inhalation Lung Injury of Rats via Activating PI3K/Akt/Nrf2 and Repressing FoxO1-NLRP3 Inflammasome
por: Fu, Zhonghua, et al.
Publicado: (2021)

Saikosaponin D Rescues Deficits in Sexual Behavior and Ameliorates Neurological Dysfunction in Mice Exposed to Chronic Mild Stress
por: Wang, Zhuo, et al.
Publicado: (2021)

Gallic Acid Inhibits Bladder Cancer T24 Cell Progression Through Mitochondrial Dysfunction and PI3K/Akt/NF-κB Signaling Suppression
por: Zeng, Maolin, et al.
Publicado: (2020)

Neferine Ameliorates Sepsis-Induced Myocardial Dysfunction Through Anti-Apoptotic and Antioxidative Effects by Regulating the PI3K/AKT/mTOR Signaling Pathway
por: Qi, Zhen, et al.
Publicado: (2021)

Activation of CNR1/PI3K/AKT Pathway by Tanshinone IIA Protects Hippocampal Neurons and Ameliorates Sleep Deprivation-Induced Cognitive Dysfunction in Rats
por: Li, Zi-Heng, et al.
Publicado: (2022)

The Protective Effects of Shengmai Formula Against Myocardial Injury Induced by Ultrafine Particulate Matter Exposure and Myocardial Ischemia are Mediated by the PI3K/AKT/p38 MAPK/Nrf2 Pathway
por: Chen, Lina, et al.
Publicado: (2021)

Cajanol Sensitizes A2780/Taxol Cells to Paclitaxel by Inhibiting the PI3K/Akt/NF-κB Signaling Pathway
por: Sui, Ming, et al.
Publicado: (2021)

Corrigendum: Neferine Ameliorates Sepsis-Induced Myocardial Dysfunction Through Anti-Apoptotic and Antioxidative Effects by Regulating the PI3K/AKT/mTOR Signaling Pathway
por: Qi, Zhen, et al.
Publicado: (2022)

The improvement of Coreopsis tinctoria essential oil on learning and memory impairment of d-galactose-induced mice through Nrf2/NF-κB pathway
por: Qu, Yan, et al.
Publicado: (2022)

Wogonin Attenuates Isoprenaline-Induced Myocardial Hypertrophy in Mice by Suppressing the PI3K/Akt Pathway
por: Qian, Weichun, et al.
Publicado: (2018)

Activation of PI3K/AKT/mTOR Pathway Causes Drug Resistance in Breast Cancer
por: Dong, Chao, et al.
Publicado: (2021)

Adiponectin Attenuates Lipopolysaccharide-induced Apoptosis by Regulating the Cx43/PI3K/AKT Pathway
por: Liu, Luqian, et al.
Publicado: (2021)

Eldecalcitol prevents muscle loss by suppressing PI3K/AKT/FOXOs pathway in orchiectomized mice
por: Zhang, Haichao, et al.
Publicado: (2022)

Nrf2/ARE Pathway Modulation by Dietary Energy Regulation in Neurological Disorders
por: Vasconcelos, Andrea Rodrigues, et al.
Publicado: (2019)

Resveratrol Attenuates High Glucose-Induced Osteoblast Dysfunction via AKT/GSK3β/FYN-Mediated NRF2 Activation
por: Xuan, Yue, et al.
Publicado: (2022)

An Integrated Approach Based on Network Analysis Combined With Experimental Verification Reveals PI3K/Akt/Nrf2 Signaling Is an Important Way for the Anti-Myocardial Ischemia Activity of Yi-Qi-Tong-Luo Capsule
por: Duan, Huxinyue, et al.
Publicado: (2022)

Stimulation of GLP-1 Receptor Inhibits Methylglyoxal-Induced Mitochondrial Dysfunctions in H9c2 Cardiomyoblasts: Potential Role of Epac/PI3K/Akt Pathway
por: Nuamnaichati, Narawat, et al.
Publicado: (2020)

Shexiang Tongxin Dropping Pills Promote Macrophage Polarization-Induced Angiogenesis Against Coronary Microvascular Dysfunction via PI3K/Akt/mTORC1 Pathway
por: Lu, Xiangyu, et al.
Publicado: (2022)

Anti-depression effectiveness of essential oil from the fruits of Zanthoxylum bungeanum maxim. on chronic unpredictable mild stress-induced depression behavior in mice
por: Tang, Dandan, et al.
Publicado: (2022)

Calcium Dobesilate Restores Autophagy by Inhibiting the VEGF/PI3K/AKT/mTOR Signaling Pathway
por: Wang, Yue, et al.
Publicado: (2019)

Carvacrol Attenuates Diabetic Cardiomyopathy by Modulating the PI3K/AKT/GLUT4 Pathway in Diabetic Mice
por: Hou, Ning, et al.
Publicado: (2019)

Rosmarinic Acid Ameliorates Pulmonary Ischemia/Reperfusion Injury by Activating the PI3K/Akt Signaling Pathway
por: Luo, Wenbin, et al.
Publicado: (2022)

Sanghuang Tongxie Formula Ameliorates Insulin Resistance in Drosophila Through Regulating PI3K/Akt Signaling
por: Cao, Xuqing, et al.
Publicado: (2022)

Azoxystrobin induces apoptosis via PI3K/AKT and MAPK signal pathways in oral leukoplakia progression
por: Li, Lingyu, et al.
Publicado: (2022)

Icariin Protects Bone Marrow Mesenchymal Stem Cells Against Iron Overload Induced Dysfunction Through Mitochondrial Fusion and Fission, PI3K/AKT/mTOR and MAPK Pathways
por: Yao, Xudong, et al.
Publicado: (2019)

Ferulic Acid Ameliorates Lipopolysaccharide-Induced Barrier Dysfunction via MicroRNA-200c-3p-Mediated Activation of PI3K/AKT Pathway in Caco-2 Cells
por: He, Shasha, et al.
Publicado: (2020)

Ligustilide Attenuates Ischemia Reperfusion-Induced Hippocampal Neuronal Apoptosis via Activating the PI3K/Akt Pathway
por: Wu, Qian, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_m8ksnctlf79clgiavhigdcem2s