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Combination of Oligofructose and Metformin Alters the Gut Microbiota and Improves Metabolic Profiles, Contributing to the Potentiated Therapeutic Effects on Diet-Induced Obese Animals

Accumulating studies implicate that the metformin (MET)- and oligofructose (OFS)-altered gut microbiota may play roles in the improvement of type 2 diabetes mellitus (T2DM) and obesity. However, whether the combined administration of OFS and MET could effectively affect the gut microbiota and improv...

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Detalles Bibliográficos
Autores principales: Li, Qingzhong, He, Rui, Zhang, Fengmei, Zhang, Jian, Lian, Shihai, Liu, Hongxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052043/
https://www.ncbi.nlm.nih.gov/pubmed/32158428
http://dx.doi.org/10.3389/fendo.2019.00939