Hydroxygenkwanin Inhibits Class I HDAC Expression and Synergistically Enhances the Antitumor Activity of Sorafenib in Liver Cancer Cells

Abnormal histone deacetylase (HDAC) expression is closely related to cancer development and progression. Many HDAC inhibitors have been widely used in cancer treatment; however, severe side effects often limit their clinical application. In this study, we attempted to identify natural compounds with...

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Detalles Bibliográficos
Autores principales: Chen, Chi-Yuan, Chen, Chin-Chuan, Chuang, Wen-Yu, Leu, Yann-Lii, Ueng, Shir-Hwa, Hsueh, Chuen, Yeh, Chau-Ting, Wang, Tong-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052045/
https://www.ncbi.nlm.nih.gov/pubmed/32158695
http://dx.doi.org/10.3389/fonc.2020.00216

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052045/
https://www.ncbi.nlm.nih.gov/pubmed/32158695
http://dx.doi.org/10.3389/fonc.2020.00216

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